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- Redação de Documentos Académicos e CientíficosPublication . Cunha, Agostinho; Jesus, Ângelo; Oliveira, Ana Isabel; Silva, Ana Luísa; Madureira-Carvalho, Áurea; Gomes, Bruno; Pinho, Cláudia; Silva, Diana Dias da; Moreira, Fernando; Barreto, João Francisco; Santos, Marlene; Correia, Patrícia; Oliveira, Rita Ferraz; Azevedo, Rui; Ferreira, Sónia; Lima, Teresa; Jacinto, Tiago; Dias da Silva, Diana Cristina; Moreira, Fernando; Barreto, João Francisco; Santos, Marlene; Correia, Patrícia Carla dos Santos Correia; Ferraz Oliveira, RitaO livro, Redação de Documentos Académicos e Científicos pretende ser um manual abrangente e de apoio aos estudantes na produção de documentos de qualidade. Combina a teoria e a prática para responder às necessidades do percurso académico nas Ciências da Saúde. Encontra-se dividido em duas partes. A primeira parte aborda os fundamentos da comunicação científica: tipologias de trabalho, normas de formatação, estruturação de documentos e o processo de submissão e revisão de artigos. Inclui ainda capítulos essenciais sobre ética na investigação, combate ao plágio, identificação de revistas predatórias e compreensão de indicadores bibliométricos. A segunda parte apresenta orientações específicas para diferentes tipos de documentos: relatórios de estágio e laboratoriais, resumos científicos, posters, comunicações orais, projetos de investigação, artigos científicos e documentos de candidatura profissional (CV e cartas de apresentação). Com exemplos práticos, esquemas, diagramas e várias sugestões, o livro constitui uma ferramenta de consulta permanente, adequada tanto à aprendizagem inicial como ao aperfeiçoamento dos mais experientes. Este manual foi escrito por docentes e especialistas de várias áreas e instituições, num exercício de sinergia que pretende responder às especificidades do contexto académico nacional e europeu, preenchendo uma lacuna importante na literatura, em português, sobre comunicação científica.
- Proceedings of Research and Practice in Allied and Environmental Health 2023 - XVIII Colóquio de Farmácia: Papel da Farmácia em OncologiaPublication . Pinho, Cláudia; Cruz, Agostinho; Oliveira, Ana Isabel; Jesus, Ângelo; Moreira, Fernando; Santos, Marlene; Correia, Patrícia; Ferraz Oliveira, RitaO evento, que conta já com a sua 18ª edição, foi um espaço privilegiado para partilhar, evidenciar e debater o que se investiga e faz em áreas prioritárias e desafiantes da Farmácia, como a Oncologia no contexto de Farmácia Comunitária e Hospitalar. Pretendeu, ainda, ser um momento de troca de opiniões e de experiências entre os participantes, académicos, investigadores e profissionais.
- Processo de auto-avaliação na Escola Superior de Tecnologia da Saúde (ESTSP): Um desafio enquadrado no espírito da Declaração de BolognaPublication . Fonte, Rosália; Prudêncio, CristinaAtendendo ao espírito da Declaração de Bologna, a livre circulação que determina a mobilidade de pessoas e a decorrente possibilidade de emprego nos países da U.E., pressupõe que sejam tomados em consideração conhecimentos, capacidades e competências, através do reconhecimento e validação dos diplomas obtidos nos países de origem. Para que tal aconteça é necessário que a qualidade dos diplomas seja garantida pelas Instituições de Ensino Superior (IES) através da Auto-Avaliação e pela Entidade que, a nível nacional, é responsável pelo sistema de qualidade, através da Avaliação externa (Andrade, 2003).
- Relação entre os conhecimentos adquiridos pelos alunos e as metodologias e estratégias por eles utilizadas para o estudo da Bioquímica em Ciências da SaúdePublication . Prudêncio, Cristina; Ferraz, Ricardo; Fonte, RosáliaNum contexto de reestruturação da formação em Ciências da Saúde baseada em competências, torna-se necessário avaliar como e quais as competências realmente adquiridas pelos alunos, logo desde o primeiro ano. O conhecimento e o saber são a primeira etapa para a prática1, constituindo aqueles que são realmente adquiridos, um pilar fundamental para uma eficaz aquisição de competências. No presente trabalho apresenta-se um estudo preliminar que pretende avaliar os conhecimentos adquiridos na disciplina de Bioquímica do 1.º ano de diferentes cursos de Tecnologias da Saúde, quer de carácter laboratorial (Análises Clínicas e Saúde Pública; Anatomia Patológica, Citológica e Tanatológica; Farmácia), quer de carácter não laboratorial (Cardiopneumologia; Medicina Nuclear; Neurofisiologia; Radiologia, Radioterapia). Adicionalmente, pretende-se estudar as metodologias e estratégias utilizadas pelos alunos para o estudo da disciplina, enquadrada numa metodologia de ensino tradicional com 3h teóricas/semana (para os cursos laboratoriais ainda com 2h práticas/semana), avaliando uma potencial relação entre os conhecimentos adquiridos e a sua forma de estudo.
- The impact of the COVID-19 pandemic in social workers’ quality of life—A study casePublication . Azevedo, Rui; Moreto, Joana; Sá, Maria ManuelQuality of life is associated with physical health, psychological state, level of independence, social relationships, personal beliefs and their relationship to salient features of their environment, reporting to a subjective evaluation, embedded in a cultural, social, environmental and professional context. On the other hand, some authors argue that people’s quality of life depends on their access to certain social and economic goods and services that naturally vary depending on the culture the subjects are inserted in. The pandemic brought about nefarious consequences to people’s routines and their quality of life. Some companies stopped or reduced production, and adopted telework, facing the governmental measures that emerged to tackle the pandemic. However, most IPSSs (Private Social Solidarity Institutions) kept with their work, which lead to physical and emotional burnout. This study aims to assess the impact of the COVID-19 pandemic in the quality of life of IPSS workers, using the WHOQOL-BREF scale. We have found that workers hold a “reasonable” perception both of their quality of life and the state of their health. The physical, social and environmental domains, which were defined as facets of quality of life, were rated between “reasonable” and “good”. The psychological domain was rated the lowest, with a “reasonable” rate. We were able to establish a negative correlation between two domains (physical and environmental) and age. Conversely, level of education was positively correlated with the physical, psychological and environmental domains.
- Optimization of an HPLC-DAD method for Quercetin detectionPublication . Carvalho, Daniel; Moreira, Fernando; Oliveira, Ana IsabelHigh-performance liquid chromatography (HPLC) is one of the most used liquid chromatographic techniques owing to its versatility that allows an optimal resolution. Quercetin (QUE), a polyphenol, has received increasing attention due to its antioxidant properties. Efforts have been made to overcome the traditional poor oral bioavailability of quercetin, requiring the development of analytical techniques for quercetin detection in different matrices. The main objective of this work was the optimization of a HPLC-Diode Array Detector (DAD) method for quercetin. An optimization process was conducted to guarantee the best conditions and results. Detection and quantification were executed with a reverse phase C-18 column. Different mobile phase (MP) compositions, flow rates, and wavelengths (with DAD) were studied. Better results were achieved with a MP composition of water:acetonitrile:methanol (55:40:5), with 1.5% acetic acid at a 1.3 mL/minute flow rate, with good results regarding chromatogram resolution, and quercetin quantification and detection.
- Adverse reactions mediated by Strontium-89, Samarium-153, Rhenium-186 and Rhenium-188: A Systematic Review of LiteraturePublication . Pinho, Cláudia; Martins, Sara; Jesus, Ângelo; Suárez, Ana MartínOne of the therapies used for the palliative treatment of pain associated with bone metastases is radiopharmaceutical therapy. Radiopharmaceuticals can cause adverse reactions, and, therefore, the aim is to systematize the results and conclusions of studies on the use of the radiopharmaceuticals 89Sr, 153Sm, 186Re and 188Re in the palliative treatment of pain associated with bone metastases. A systematic literature review was conducted according to PRISMA statement, using the databases MEDLINE and EBSCO. After the selection process, 20 articles were included. The studies showed that the 4 radiopharmaceuticals analysed presented very similar results regarding pain relief after treatment, decrease in analgesic consumption, side effects at the time of administration, hematologic toxicity and disease progression after treatment. Concluding, the use of radiopharmaceuticals for pain palliation seems to be safe and an alternative to existing treatments.
- PML/ RARA variants and their role in Arsenic Trioxide resistance in APL: a scoping reviewPublication . Gonçalves, Patrícia; Santos, Claúdia dos; Sousa, Maria; Mota, SandraCurrently, the treatment of Acute Promyelocytic Leukemia (APL) is grounded on therapeutic regimens based on arsenic trioxide (ATO). However, mutations in the PML component of the PML/RARA oncoprotein are believed to be involved in the mechanism of resistance to this agent. We performed a scoping review to understand the role of variant PML/RARA fusion proteins in the mechanism of resistance in APL. Applying the defined criteria, we selected 10 studies, in which patients presented a picture of relapse and/or resistance after the administration of ATO, having been identified at least one PML mutation. We also reported that RARA is the most frequently mutated gene, although we also found mutations in genes related to other processes involved in cell differentiation. Briefly, this is a multifactorial mechanism and PML/RARA variants are important but not an obligatory condition for ATO resistance to occur.
- Semi-quantitative methods for assessing the risk of occupational accidents: A literature reviewPublication . Noronha, Ana R.; Costa, Sónia L.; Ferreira, Adriana S.; Faria, Brígida Mónica; Vieira da Silva, Manuela; Rodrigues, MatildeThis study reviewed the existing literature on the application of semi-quantitative methods to assess the risk of occupational accidents. The main goal was to identify and describe the methods used in practical applications. PRISMA methodology was applied in this systematic literature review. Scientific articles were searched in Science Direct, PubMed and B-on (from 2010 until March 2022). After defining and applying the inclusion and exclusion criteria, 3 articles were analyzed. It should be noted the limited availability of articles that describe the application of semi-quantitative methods to assess the risk of occupational accidents. Given its advantages in decision-making about risk acceptance and the need of control measures, we highlight the importance of future developments of these methods and the need to expand their practical applicability.
- Cyanobacteria in cosmetics: a natural alternative for anti-aging ingredientsPublication . Morone, Janaína; Lopes, Graciliana; Oliveira, Beatriz; Vasconcelos, Vítor; Martins, RosarioBeing exposed to endogenous and exogenous stressors, and being the body’s external defense line, skin protection is of pivotal importance, in order to maintain morphological and physiologic integrity and health. Fostering by individual psychological comfort, esthetic performance, and young appearance, along with motivation for natural products with less side effects and sustainable production, consumer’s demands drive the cosmetic industry into the relentless pursuit for innovation. In this context, cyanobacteria enforce as a promising source of ingredients with cosmetic potential. With the ability to withstand adverse conditions for survival, the adaptation to extreme environments is reflected in the production of compounds with moisturizing, photoprotective, antioxidant, and whitening potential, all attributes required in cosmetics, namely in anti-aging products. In this chapter, we will focus on the interconnection between cyanobacteria and skin, by presenting the main applications of these organisms in skincare products.
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