A carregar...
Publicação
Beer raw materials: evaluation of antioxidant activity and potential skin benefits
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 149.56 KB | Adobe PDF |
Orientador(es)
Resumo(s)
Malt and hop extracts have shown promising skin benefits, but scientific evidence is scarce. To evaluate, in vitro, the potential of aqueous extracts of malt and hops for antioxidant, photoprotective and metabolic activity in human keratinocytes (HaCaT cells). Experimental study, with the preparation of aqueous extracts of three malts (Chocolate, Munich and Vienna) and hops (Saaz, Citra and Mosaic), according to Silva et al. (2022). Total of phenolic compounds (TPC), antioxidant (hydrogen peroxide neutralization assay), photoprotective (sun protection factor- SPF), and metabolic activity of HaCaT cells (3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2Htetrazolium bromide -MTT assay) were evaluated. Data were analysed using the one-way ANOVA test and significant differences were considered for p < 0.05. The aqueous extracts of hops showed higher TPC (54.20± 1.56 - 90.02±0.48 mg GAE/g), antioxidant (1.88±0.11 < IC50 < 3.81±0.15 μg/mL) and photoprotective activity (173.77±2.75 < SPF < 213.97±4.77), compared to malt extracts (10.97±0.48 < TPC < 21.18±0.40 mg GAE/g, 11.67±0.63 < IC50 < 17.63±0.46 μg/mL and 21.22±0.12 < SPF < 79.53±0.93) (p < 0.05). Generally, cell viability was higher than 80% at the concentrations tested (1 - 500 μg/mL). The hop extracts had higher cell viabilities than the control (culture medium), showing greater potential for skin regeneration. Saaz hops have the highest TPC and SPF (p < 0.05). The extracts show promising activities, mainly hops extracts, at the cutaneous level, but further studies are needed to corroborate the activities studied and the possibility of integrating them into cosmetic formulation.
Descrição
Palavras-chave
Malt Hop Skin
Contexto Educativo
Citação
Pereira, M. J., Santos, D., Pinho, C., & Oliveira, A. I. (2025). Beer raw materials: Evaluation of antioxidant activity and potential skin benefits. 13th APLF Annual Conference, TherapeuTic advances in drug safety 16(S1), 61–62. https://journals.sagepub.com/doi/epub/10.1177/20420986251379201
Editora
SAGE Publications