Browsing by Author "Adubeiro, Nuno"
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- Acute effects of physical exercise with microcurrent in the adipose tissue of the abdominal region: A randomized controlled trialPublication . Noites, Andreia; Moreira, Anabela; Melo, Cristina; Faria, Miriam; Vilarinho, Rui; Freitas, Carla; Monteiro, Pedro; Carvalho, Paulo; Adubeiro, Nuno; Sousa, Maria; Santos, Rubim; Nogueira, LuisaIncreased abdominal fat and sedentary lifestyles contribute to cardiovascular disease risk. Low-intensity electrical current (microcurrent) on the abdominal region, associated with physical exercise, appears to be an innovative method to increase the lipolytic rate of abdominal adipocytes, in order to reduce abdominal fat. This study aimed to analyze the acute effects of microcurrent associated with an aerobic exercise program in healthy subjects in lipolysis. A double-blinded, randomized controlled trial was developed and conducted in a higher education school. Eighty-three healthy subjects, aged between 18 and 30 years old and with a 18.5 to 29.9 kg/m2 body mass index were randomly assigned either to an experimental or to a placebo group. Subjects received a trans-abdominal microcurrent stimulation for 40 min with (experimental group) or without (placebo group) electrical current, followed by a single aerobic exercise session (60 min at 45–55% VO2max intensity). Lipolytic activity (serum glycerol), abdominal fat (waist circumference, abdominal skinfold, ultrasonography), and serum lipid profile (serum triglyceride, total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol) were evaluated in all subjects. Physical activity (International Physical Activity Questionnaire) and dietary intake (food-frequency questionnaire) questionnaires were applied. After the intervention, lipolytic rate was significantly higher (p = 0.003) in the experimental group (mean = 0.15) than in the placebo group (mean = 0.09). Glycerol results showed a statistically significant increase between baseline and after the intervention for both experimental group (p = 0.001) and the placebo group (p = 0.001). Combined use of microcurrent and physical aerobic exercise had an acute effect enhancing lipolytic rate comparing to exercise alone, in young healthy subjects.
- Apparent diffusion coefficient in the analysis of prostate cancerPublication . Adubeiro, Nuno; Nogueira, Luísa; Ribeiro, Eduardo; Alves, Sandra; Ferreira, Hugo; La Fuente, JoséThe multiparametric magnetic resonance imaging (MPMRI) approach, has allowed the diagnostic performance in the detection and characterization of prostate cancer (PCa). Diffusion-weighted imaging (DWI), is an important technique in the MPMRI, that provides qualitative and quantitative biological information regarding water diffusivity in a non-invasive manner. The apparent diffusion coefficient (ADC) measures water mobility and can be quantified from the signal intensity loss between two or more b-values. Different studies reported that ADC values are directly associated with microvessel density and cellularity. One of the main aspects that is in discussion is the b-values that must be used in the DWI sequence in order to compute ADC.
- Apparent diffusion coefficient in the analysis of prostate cancer: determination of optimal b-value pair to differentiate normal from malignant tissuePublication . Adubeiro, Nuno; Nogueira, Maria Luísa; Nunes, Rita G.; Ferreira, Hugo Alexandre; Ribeiro, Eduardo; La Fuente, José Maria FerreiraPurpose Determining optimal b-value pair for differentiation between normal and prostate cancer (PCa) tissues. Methods Forty-three patients with diagnosis or PCa symptoms were included. Apparent diffusion coefficient (ADC) was estimated using minimum and maximum b-values of 0, 50, 100, 150, 200, 500 s/mm2 and 500, 800, 1100, 1400, 1700 and 2000s/mm2, respectively. Diagnostic performances were evaluated when Area-under-the-curve (AUC) > 95%. Results 15 of the 35 b-values pair surpassed this AUC threshold. The pair (50, 2000 s/mm2) provided the highest AUC (96%) with ADC cutoff 0.89 × 10–3 mm2/s, sensitivity 95.5%, specificity 93.2% and accuracy 94.4%. Conclusions The best b-value pair was b = 50, 2000 s/mm2.
- Associations between nutrition, energy expenditure and energy availability with bone mass acquisition in dance students: a 3-year longitudinal studyPublication . Amorim, Tânia; Freitas, Laura; Metsios, George S.; Thayse, Natacha Gomes; Wyon, Matthew; Flouris, Andreas D.; Maia, José; Marques, Franklim; Nogueira, Luísa; Adubeiro, Nuno; Koutedakis, YiannisThree years of study showed that female and male vocational dancers displayed lower bone mass compared to controls, at forearm, lumbar spine and femoral neck. Energy intake was found to positively predict bone mass accruals only in female dancers at femoral neck. Vocational dancers can be a risk population to develop osteoporosis.
- Avaliação dos resultados da aplicação combinada do ultrassom e da drenagem linfática manual no fibro-edema gelóidePublication . Rodrigues, Elisa; Lopes, André; Adubeiro, Nuno; Faria, MiriamO fibro-edema gelóide (FEG), popularmente conhecido como celulite, é uma alteração comum da topografia da pele que reflete disfunções precoces nos sistemas vascular e/ou metabólico e conjuntivo, afetando milhões de pessoas no mundo, predominantemente mulheres. A partir de perspetivas em saúde cada vez mais holísticas e integrativas, poder-se-á usar o FEG como indicador precoce para doenças cardiovasculares e metabólicas. As terapias eficazes podem ser chaves no diagnóstico dos principais sistemas disfuncionantes envolvidos. Muitos métodos são utilizados no seu tratamento, entre os quais se incluem a drenagem linfática manual (DLM) e o ultrassom.
- Avaliação radiológica do refluxo vesico – ureteral em criançasPublication . Nogueira, Luísa; Caldeira, J. P.; Adubeiro, NunoO Refluxo Vesico – Ureteral (RVU) é uma patologia frequente na idade pediátrica. A detecção precoce de RVU é fundamental na orientação terapêutica, de modo a permitir um crescimento renal adequado e prevenir infecções urinárias recorrentes. A investigação radiológica de RVU baseia-se na ecografia e cistouretrografia miccional seriada (CUMS), sendo este último procedimento, o método de eleição, efectuado sob controlo fluoroscópico. Este trabalho tem como objectivo dar a conhecer o papel CUMS na avaliação de RVU e abordar os parâmetros técnicos de aquisição, posicionamento e critérios de qualidade de imagem.
- Body mass index and visceral fat: correlation with serum lipid profile in healthy young adultsPublication . Moreira, Anabela; Noites, Andreia; Couto, Miriam; Vilarinho, Rui; Melo, Cristina; Sousa, Manuela; Monteiro, Pedro; Carvalho, Paulo; Adubeiro, Nuno; Nogueira, Luisa; Santos, RubimMetabolic and cardiovascular complications and obesity association is well described. Body mass index (BMI) is commonly used to assess obesity, but does not reflect body fat distribution. Abdominal obesity, namely visceral adipose tissue (VAT), is associated with greater risk for those metabolic impairments, including dyslipidemia, than adiposity in other regions of the body. Objective: To determine the correlation between serum lipid profile and anthropometric measures (BMI and VAT) in young healthy adults.
- Bone mineral density in vocational and professional ballet dancersPublication . Amorim, T.; Koutedakis, Y.; Nevill, A.; Wyon, M.; Maia, J.; Machado, J. C.; Marques, F.; Metsios, G.S.; Flouris, A.D.; Adubeiro, Nuno; Nogueira, L.; Dimitriou, L.According to existing literature, bone health in ballet dancers is controversial. We have verified that, compared to controls, young female and male vocational ballet dancers have lower bone mineral density (BMD) at both impact and non-impact sites, whereas female professional ballet dancers have lower BMD only at non-impact sites.
- Diffusion MRI outside the brainPublication . Nunes, Rita G.; Nogueira, Luisa; Gaspar, Andreia S.; Adubeiro, Nuno; Brandão, SofiaThis manuscript provides an overview of recent developments in Diffusion-Weighted Imaging (DWI) outside the brain, focusing on liver, breast, prostate, muskuloskeletal (MSK) and cardiac applications. A general introduction to cross-cutting acquisition and image processing challenges is first provided. These often include short T2 relaxation times, the need to image a large field-of-view with the resulting complications in shimming the B0 field and achieving good fat suppression. Some of the strategies developed for dealing with motion, namely cardiac and respiratory motion are described. Specific sections are then presented for each of the aforementioned organs. A motivation for the clinical applicability of DWI is first provided, followed by specific image acquisition and processing considerations. Quantitative imaging is becoming standard in clinical practice, and the Apparent Diffusion Coefficient is routinely estimated in the liver, breast and prostate. Application of alternative signal models in these organs is being explored, including both the Intravoxel Incoherent Motion and Diffusion Kurtosis models. Ongoing efforts are focused on evaluating the potential clinical added value of the extra parameters and on improving their repeatability. MSK and cardiac DWI have shown potential for assessing pathological changes in fiber architecture, but further validation is required to enable application in the clinical setting.
- Dual source/dual energy-renal applicationsPublication . Adubeiro, Nuno; Nogueira, Luísa; Guedes, Mónica; Pinho, ErnestoDevelopment of Dual Source Computed Tomography (Definition, Siemens Medical Solutions, Erlanger, Germany) allowed advances in temporal resolution, with the addition of a second X-ray source and an array of detectors to the TCM 64 slices. The ability to run exams on Dual Energy, allows greater differentiation of tissues, showing differences between closer attenuation coefficients. In terms of renal applications, the distinction of kidney stones and masses become one of the main advantages of the use of dual-energy technology. This article pretends to demonstrate operating principles of this equipment, as its main renal applications.
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