Apparent diffusion coefficient in the analysis of prostate cancer

Adubeiro, Nuno; Nogueira, Luísa; Ribeiro, Eduardo; Alves, Sandra; Ferreira, Hugo; La Fuente, José

http://hdl.handle.net/10400.22/20039

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Abstract(s)

The multiparametric magnetic resonance imaging (MPMRI) approach, has allowed the diagnostic performance in the detection and characterization of prostate cancer (PCa). Diffusion-weighted imaging (DWI), is an important technique in the MPMRI, that provides qualitative and quantitative biological information regarding water diffusivity in a non-invasive manner. The apparent diffusion coefficient (ADC) measures water mobility and can be quantified from the signal intensity loss between two or more b-values. Different studies reported that ADC values are directly associated with microvessel density and cellularity. One of the main aspects that is in discussion is the b-values that must be used in the DWI sequence in order to compute ADC.

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http://hdl.handle.net/10400.22/20039

Citation

Adubeiro, N., Nogueira, L., Ribeiro, E., Alves, S., Ferreira, H., & La Fuente, J. (2015). Apparent diffusion coefficient in the analysis of prostate cancer. In R. A. Silva, P. Baylina, F. Q. Vieira, C. Barrias, M. Rubim, T. Coelho, C. Prudêncio, & Â. Jesus (Eds.), II Congresso Internacional da Saúde Gaia Porto: Livro de Resumos (1 st ed., Vol. 1, pp. 70). Escola Superior de Tecnologia da Saúde do Instituto Politécnico do Porto.