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Advisor(s)
Abstract(s)
Purpose
Determining optimal b-value pair for differentiation between normal and prostate cancer (PCa) tissues.
Methods
Forty-three patients with diagnosis or PCa symptoms were included. Apparent diffusion coefficient (ADC) was estimated using minimum and maximum b-values of 0, 50, 100, 150, 200, 500 s/mm2 and 500, 800, 1100, 1400, 1700 and 2000s/mm2, respectively. Diagnostic performances were evaluated when Area-under-the-curve (AUC) > 95%.
Results
15 of the 35 b-values pair surpassed this AUC threshold. The pair (50, 2000 s/mm2) provided the highest AUC (96%) with ADC cutoff 0.89 × 10–3 mm2/s, sensitivity 95.5%, specificity 93.2% and accuracy 94.4%.
Conclusions
The best b-value pair was b = 50, 2000 s/mm2.
Description
Keywords
Diffusion weighted imaging Diffusion Magnetic Resonance Imaging Prostate Prostatic Neoplasms
Citation
Publisher
Elsevier