Publication
Apparent diffusion coefficient in the analysis of prostate cancer: determination of optimal b-value pair to differentiate normal from malignant tissue
| dc.contributor.author | Adubeiro, Nuno | |
| dc.contributor.author | Nogueira, Maria Luísa | |
| dc.contributor.author | Nunes, Rita G. | |
| dc.contributor.author | Ferreira, Hugo Alexandre | |
| dc.contributor.author | Ribeiro, Eduardo | |
| dc.contributor.author | La Fuente, José Maria Ferreira | |
| dc.date.accessioned | 2019-06-27T16:42:00Z | |
| dc.date.available | 2019-06-27T16:42:00Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Purpose Determining optimal b-value pair for differentiation between normal and prostate cancer (PCa) tissues. Methods Forty-three patients with diagnosis or PCa symptoms were included. Apparent diffusion coefficient (ADC) was estimated using minimum and maximum b-values of 0, 50, 100, 150, 200, 500 s/mm2 and 500, 800, 1100, 1400, 1700 and 2000s/mm2, respectively. Diagnostic performances were evaluated when Area-under-the-curve (AUC) > 95%. Results 15 of the 35 b-values pair surpassed this AUC threshold. The pair (50, 2000 s/mm2) provided the highest AUC (96%) with ADC cutoff 0.89 × 10–3 mm2/s, sensitivity 95.5%, specificity 93.2% and accuracy 94.4%. Conclusions The best b-value pair was b = 50, 2000 s/mm2. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.1016/j.clinimag.2017.09.004 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.22/14138 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Elsevier | pt_PT |
| dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S0899707117301705 | pt_PT |
| dc.subject | Diffusion weighted imaging | pt_PT |
| dc.subject | Diffusion Magnetic Resonance Imaging | pt_PT |
| dc.subject | Prostate | pt_PT |
| dc.subject | Prostatic Neoplasms | pt_PT |
| dc.title | Apparent diffusion coefficient in the analysis of prostate cancer: determination of optimal b-value pair to differentiate normal from malignant tissue | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 95 | pt_PT |
| oaire.citation.startPage | 90 | pt_PT |
| oaire.citation.title | Clinical Imaging | pt_PT |
| oaire.citation.volume | 47 | pt_PT |
| person.familyName | Adubeiro | |
| person.givenName | Nuno | |
| person.identifier.ciencia-id | 0119-2885-C797 | |
| person.identifier.orcid | 0000-0001-8657-3288 | |
| person.identifier.rid | AAC-1663-2021 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 35d1aa21-3c2a-4af6-8346-efa61cd513fc | |
| relation.isAuthorOfPublication.latestForDiscovery | 35d1aa21-3c2a-4af6-8346-efa61cd513fc |