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Advisor(s)
Abstract(s)
(Introduction) Novel application Plastic Antibody that responds to a cardiac biomarker, myoglobin (Myo). Imprint stage with electropolymerization of ortho-phenylenediamine (OPD) in the presence of Myo. Template removal from polymeric matrix digested by trypsin. The films acted as biomimetic artificial antibodies and were fabricated on a screen-printed platinium (Pt) electrode (SPE) modified with electroactive Prussian blue nanocubes (PBNCs) to take a step towards disposable sensors for point-of-care applications. The devices showed linear responses to Myo in SWV assays up to 0.01 and 10000 ng/mL.
Description
The authors would like to acknowledge the partial support of the Portuguese Foundation for Science and Technology (FCT), through grants UIDB/04730/2020 and UIDP/04730/2020. This study was financed by project IBEROS+ (0072_IBEROS_MAIS_1_E, Interreg-POCTEP 2021-2027).
Keywords
Plastic antibodies Diagnosis Myocardial infarction
Citation
Ricardo, J., Martins, G., & Moreira, F.T.C. (2024, Jun. 14). Plastic antibody for the diagnosis of acute myocardial infarction [Poster presentation]. IBEROS+ - II Jornadas do Instituto de Biofabricação em Rede para o Envelhecimento Saudável, Porto, Portugal