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Ecotoxicity of valproic acid in Lemna minor

dc.contributor.authorMachado, Beatriz
dc.contributor.authorPrudêncio, Cristina
dc.contributor.authorFerraz, Ricardo
dc.contributor.authorBarros, Piedade
dc.date.accessioned2024-05-08T11:47:17Z
dc.date.available2024-05-08T11:47:17Z
dc.date.issued2023-07-09
dc.description.abstractThe water pollution represents one of the most serious ecological challenges. Over the last years the use and consumption of pharmaceuticals has increased,and this is reflected in the rise of water contamination. Many drugs cannot be efficiently removed by wastewater treatment and ended up being released into the aquatic environment. Valproic acid is an anticonvulsive and mood stabilizer medication that has been found in the aquatic environment. Although some effects of this drug on small mammals and fish are known, its ecotoxicity in plants has not yet been evaluated. Lemnaminor is widely used as a bioindicator of water quality. This aquatic macrophyte has been applied for remediation studies and has shown effective results. The aim of this study is to study the ecotoxicity of valproic acid on the growth of Lemna minor. Lemna minor was exposed to six different concentrations of valproic acid for 7 days. During this time the number of fronds was analyzed. After the test some parameters were evaluated: area of fronds, root length and chlorophylls content. The chlorophylls were analyzed by spectrophotometry. At the higher concentration (0,1 mg/L) of valproic acid, the number of fronds was significantly lower than the control. Also, chlorophyll content was lower at 0,05 mg/L and 0,1 mg/Lfor chlorophyll a, b and carotenoids and at 0,025mg/L; 0,05mg/L and0,1mg/L for total chlorophyll. The rootlength was significantly lower at the higher concentrations(0,025mg/L; 0,05mg/L and 0,1mg/L), comparatively to the control. The fronds area didn’t show any significant difference when compared to the control. Valproic acid influenced the number of fronds,length of the root and concentration of chlorophylls and at the higher concentrations it is notable a significant inhibitory effect.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMachado, B., Prudêncio, C., Ferraz, R., & Barros, P. (2023). Ecotoxicity of valproic acid in Lemna minor. Proceedings of Research and Practice in Allied and Environmental Health, 1(1), 23. https://doi.org/10.26537/prpaeh.v1i1.5179pt_PT
dc.identifier.doi10.26537/prpaeh.v1i1.5179pt_PT
dc.identifier.issn2975-9420
dc.identifier.urihttp://hdl.handle.net/10400.22/25480
dc.language.isoengpt_PT
dc.publisherEscola Superior de Saúde - IPP Portopt_PT
dc.relation.publisherversionhttps://parc.ipp.pt/index.php/PRPAEH/article/view/5179pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectDuckweedpt_PT
dc.subjectLemna minorpt_PT
dc.subjectValproic acidpt_PT
dc.subjectWater contaminationpt_PT
dc.titleEcotoxicity of valproic acid in Lemna minorpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePortopt_PT
oaire.citation.startPage23pt_PT
oaire.citation.titleProceedings of Research and Practice in Allied and Environmental Health 2023pt_PT
oaire.citation.volume1 (1)pt_PT
person.familyNameMachado
person.familyNamePrudêncio
person.familyNameFerraz
person.familyNameGonçalves de Barros
person.givenNameBeatriz
person.givenNameCristina
person.givenNameRicardo
person.givenNamePiedade Aurora
person.identifier1200571
person.identifier.ciencia-idC81E-F4EE-FADE
person.identifier.ciencia-id001E-71CE-F92D
person.identifier.ciencia-idD210-6003-454B
person.identifier.orcid0009-0007-3666-5468
person.identifier.orcid0000-0002-9920-936X
person.identifier.orcid0000-0002-1761-117X
person.identifier.orcid0000-0002-2635-251X
person.identifier.ridG-5639-2011
person.identifier.scopus-author-id6508057930
person.identifier.scopus-author-id24464208500
person.identifier.scopus-author-id23981959400
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationd0c058b5-ffb7-4a9a-80a3-a96a9acddbfa
relation.isAuthorOfPublication881a8ad5-ab13-4e49-89f4-08ca61cc81e3
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relation.isAuthorOfPublicationa85b368a-8f13-45eb-a744-7c5810a38e2c
relation.isAuthorOfPublication.latestForDiscovery881a8ad5-ab13-4e49-89f4-08ca61cc81e3

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