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Efficacy and safety of dry extract Hedera helix in the treatment of productive cough

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One of the most frequent symptoms in medical practice is cough. Consequently, there is a wide range of products available for its treatment, not only drugs but also some herbal products. This work focuses on the dry extract of Hedera helix, which increasingly gains popularity. Systematize the scientific evidence on the efficacy and safety of Hedera helix extract in the treatment of productive cough. Systematic review, using databases Pubmed, EBSCO and Science Direct. Articles were selected in English, Spanish and Portuguese and with no more than twenty years since publication. Ten studies were selected, consisting of 69310 individuals with varying ages. One study was placebo controlled. Four studies compared different formulations with extract. One study analysed differences between the treatment with the dry extract of Hedera helix compared with the conventional therapy. Three open non-comparative multi-centre trials were also included as well as a retrospective study. All studies show evidence of the efficacy and tolerability of Hedera helix extract in the treatment of productive cough. Due to the minimal incidence of adverse effects, the authors were able to admit a good tolerability of ivy extract. The studies included in this review indicate that Hedera helix dry extract preparations have positive effects in productive cough, showing improvement in terms of respiratory function in patients with diseases of the respiratory tract. However, more robust studies are required for a structured evaluation of the safety and tolerability of this extract in productive cough.

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Hedera helix cough ivy alpha-hederin

Citation

Costa, Jesus, Â., Cardoso, A., Meireles, A., Colaço, A., & Cruz, A. (2016). Efficacy and safety of dry extract Hedera helix in the treatment of productive cough. Proceedings of the 3rd IPLeiria’s International Health Congress - BMC Health Services Research, 16 (3), 120.

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BioMed Central

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