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Orientador(es)
Resumo(s)
(Introduction) Myoglobin (Myo) is the first cardiac biomarker to be released into the bloodstream after the onset of symptoms of Acute Myocardial Infarction (AMI), allowing earlier detection of this disease. Novel application based on Plastic Antibody that responds to a cardiac biomarker, Myo. Imprint stage with electropolymerization of ortho-phenylenediamine (OPD) in the presence of Myo. Template removal from polymeric matrix digested by trypsin. The biomimetic film was fabricated on platinum screen-printed electrodes (Pt-SPE) modified with electroactive Prussian blue nanocubes (PBNCs).
Descrição
The authors acknowledge the partial support of the Portuguese Foundation for Science and Technology (FCT), through grants UIDB/04730/2020 and UIDP/04730/2020. This study was financed by project IBEROS+ (0072_IBEROS_MAIS_1_E, Interreg-POCTEP 2021-2027).
Palavras-chave
Cardiac biomarkers Symptoms of Acute Myocardial Infarction Biomimetic Myoglobin
Contexto Educativo
Citação
Ricardo, J., Martins, G.V., & Moreira, F.T.C. (2024, Jul., 3-5). Plastic antibody for the diagnosis of acute myocardial infarction [Poster presentation]. Ciência 2024 - Encontro com a Ciência e a Tecnologia em Portugal, Porto, Portugal