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Dietary supplements and cosmetics with cannabis sativa l. and/or cannabidiol: analysis of labelling information and cannabinoid quantification methods

dc.contributor.authorBatalha, Ana
dc.contributor.authorRegalo, Sandra
dc.contributor.authorOliveira, Ana Isabel
dc.contributor.authorPinho, Cláudia
dc.contributor.authorCorreia, Patrícia
dc.contributor.authorCorreia, Patrícia Carla dos Santos Correia
dc.contributor.authorPinho, Cláudia
dc.contributor.authorOliveira, Ana Isabel
dc.date.accessioned2026-09-21T13:51:10Z
dc.date.available2026-09-21T13:51:10Z
dc.date.issued2025-10
dc.description.abstractThe growing interest in the potential benefits of Cannabis sativa L. (CS) and cannabidiol, has boosted the marketing of dietary supplements (DS) and cosmetic products (CP). However, legal compliance and labelling information lack raises concerns about consumer safety [1]. Analyse labelling information on DS and CP containing CS and/or cannabidiol, available online, and review cannabinoid quantification analytical methods (CQAM). A descriptive, cross-sectional study was conducted from August to October 2024 to collect DS and CP from websites (e.g. pharmacies, herbal stores) containing CS and/or cannabidiol, isolated or in mixtures. The labelling information was analysed (uses, ingredients, interactions, adverse reactions). A literature review was conducted in December 2024 using PubMed® to gather studies about CQAM, using the keywords “Chemistry Techniques, Analytical” [Mesh], “Cannabis sativa”, “Cannabinoids”. A total of 60 products (22 DS; 38 CP) were identified. The most common ingredient was seed oil, present in 73% of DS and 59% of CP. The main indications were associated with skin hydration (16 CP), and as a complement in nervous system problems (18 DS). The literature review resulted in 16 studies. Two high-performance liquid chromatography methods were found the best for cannabinoid quantification, demonstrating good linearity, precision and accuracy. Ingredients, such as CS seed oil and cannabidiol, showed inconsistencies with current Portuguese legislation. Collected DS and CP may differ in CS and other contents, highlighting the importance of quality control and regulatory monitoring, using the validated CQAM identified in this study.eng
dc.identifier.citationBatalha, A., Regalo, S., Oliveira, A. I., Pinho, C., & Correia, P. (2025). Dietary supplements and cosmetics with cannabis sativa l. And/or cannabidiol: Analysis of labelling information and cannabinoid quantification methods. 13th APLF Annual Conference, TherapeuTic advances in drug safety 16(S1), 68–69. https://journals.sagepub.com/doi/epub/10.1177/20420986251379201
dc.identifier.doi10.1177/20420986251379201
dc.identifier.eissn2042-0994
dc.identifier.issn2042-0986
dc.identifier.urihttp://hdl.handle.net/10400.22/32757
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSAGE Publications
dc.relationUID/50006
dc.relation.hasversionhttps://journals.sagepub.com/doi/epub/10.1177/20420986251379201
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectCannabis sativa L.
dc.subjectCannabidiol
dc.subjectLabelling information
dc.titleDietary supplements and cosmetics with cannabis sativa l. and/or cannabidiol: analysis of labelling information and cannabinoid quantification methodseng
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferenceDate2025-10
oaire.citation.conferencePlaceAveiro
oaire.citation.endPage69
oaire.citation.issueS1
oaire.citation.startPage68
oaire.citation.title13th APLF Annual Conference TherapeuTic advances in drug safety
oaire.citation.volume16
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameCorreia
person.familyNamePinho
person.familyNameOliveira
person.givenNamePatrícia Carla dos Santos Correia
person.givenNameCláudia
person.givenNameAna Isabel
person.identifier.ciencia-id221F-5A5F-BFC9
person.identifier.ciencia-id8B1B-A0D9-B6E4
person.identifier.ciencia-id9212-F501-E9EF
person.identifier.orcid0000-0001-7869-7977
person.identifier.orcid0000-0002-3157-3712
person.identifier.orcid0000-0003-4420-6476
relation.isAuthorOfPublication655ab14f-f60f-42c5-8c8a-19d5257ff5f6
relation.isAuthorOfPublication01c994b8-cb20-43a8-947c-d2b978283944
relation.isAuthorOfPublication4b3fe293-2740-469f-97d3-99d0b107b5e0
relation.isAuthorOfPublication.latestForDiscovery655ab14f-f60f-42c5-8c8a-19d5257ff5f6

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