Publication
Cytotoxity induced by extracts of Pisolithustinctorius spores on human cancer and normal cell lines – evaluation of the anticancer potential
| dc.contributor.author | Alves, Ricardo | |
| dc.contributor.author | Preto, Marco | |
| dc.contributor.author | Oliveira, Rui S. | |
| dc.contributor.author | Martins, Rosário | |
| dc.date.accessioned | 2024-09-17T13:23:46Z | |
| dc.date.available | 2024-09-17T13:23:46Z | |
| dc.date.issued | 2014-09 | |
| dc.description.abstract | Cancer is one of the most important causes of death and morbidity worldwide. According to the World Health Organization 8.2 million people have died from cancer in 2012. The treatment of this fast growing disease is regarded as a major challenge in health for the XXI century. Conventional anti-cancer therapy is usually aggressive to the patients due to systemic toxicity caused by lack of specificity of the chemotherapy drugs (Kidd, 2000). This has triggered the interest of the scientific community to search for new and more effective therapies, less aggressive than conventional treatments. Used since antiquity in oriental civilizations, fungi, in particular mushrooms have been shown to limit or reverse tumor growth (Kidd, 2000). Pisolithustinctorius (Basidiomycota) is a soil fungus with world-wide distribution that it known to form ectomycorrhizal symbioses in forest ecosystems (Kope & Fortin, 1990). The sporocarps of this fungus contain Pisosterol, a triterpene that has been shown to have antitumor activity against some cancer cell lines (Montenegro et al., 2004). Nevertheless, no studies have focused on the anticancer potential of other structures such as spores and thus the anticancer potential of P. tinctorius , remains largely unknown. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Alves, R., Preto, M., Oliveira, R. S., & Martins, R. (2014). Cytotoxity induced by extracts of Pisolithustinctorius spores on human cancer and normal cell lines – evaluation of the anticancer potential. ICEH14 /3rd International Congress of Environmental Health: Proceedings Book, 1, 69–71. | pt_PT |
| dc.identifier.isbn | 978-989-20-5086-7 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/26015 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | Área Científica da Escola Superior de Tecnologia da Saúde do Instituto Politécnico do Porto | pt_PT |
| dc.relation | R.S. Oliveira wishes to acknowledge the support of Fundação para a Ciência e a Tecnologia through the research grant SFRH/BPD/85008/2012 and Fundo Social Europeu. This work was financed by national funds through Fundação para a Ciência e a Tecnologia within the scope of the Projects PEst-OE/BIA/UI4004/2014 and PEst-C/MAR/LA0015/2013. | pt_PT |
| dc.subject | Cancer | pt_PT |
| dc.subject | Basidiomycota | pt_PT |
| dc.title | Cytotoxity induced by extracts of Pisolithustinctorius spores on human cancer and normal cell lines – evaluation of the anticancer potential | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Porto | pt_PT |
| oaire.citation.endPage | 71 | pt_PT |
| oaire.citation.issue | 1ª | pt_PT |
| oaire.citation.startPage | 69 | pt_PT |
| oaire.citation.title | ICEH14 /3rd International Congress of Environmental Health: Proceedings Book | pt_PT |
| oaire.citation.volume | 1 | pt_PT |
| person.familyName | Martins | |
| person.givenName | Rosario | |
| person.identifier.ciencia-id | A919-DB40-EF10 | |
| person.identifier.orcid | 0000-0002-9882-4651 | |
| person.identifier.scopus-author-id | 21834368700 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isAuthorOfPublication | 82a7c349-c88e-450f-adc7-3331d69149cf | |
| relation.isAuthorOfPublication.latestForDiscovery | 82a7c349-c88e-450f-adc7-3331d69149cf |