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Home parenteral nutrition guidelines: Review of key recommendations and proposal for standardization

dc.contributor.authorCerqueira, Ana
dc.contributor.authorGonçalves, Daniela
dc.contributor.authorSantos, Marlene
dc.contributor.authorMoreira, Fernando
dc.contributor.authorMoreira, Fernando
dc.date.accessioned2026-09-16T09:30:08Z
dc.date.available2026-09-16T09:30:08Z
dc.date.issued2025-10
dc.description.abstractImplementing home parenteral nutrition (HPN) is a complex process, and the large number of recommendations in this area may hinder the identification of a minimum standard of care, potentially compromising patient safety [1]. This study aimed to develop a standardized set of recommendations to support healthcare professionals in the safe and effective preparation and administration of HPN. A literature review was carried out between February 2024 and June 2025 to identify guidelines published by international organisations dedicated to HPN. To assess the methodological quality and transparency of these guidelines, the validated AGREE II instrument was used [2]. Recommendations related to the preparation/administration of HPN were extracted whenever the documents achieved moderate or high scores in the domains of rigour of development and applicability. A total of 27 guidelines from 14 different organizations were evaluated. Overall, the domain concerning the scope and purpose achieved the highest score (65 ± 17%). In contrast, the lowest score was observed in the domain of editorial independence (35 ± 20%). Sixteen documents, authored by nine organizations demonstrated moderate to high quality in domains 3 and 5 and were used for the development of the standardized proposal that included as most prominent recommendations: personal protective equipment, aseptic technique, appropriate containers (for preparation) and therapy length (for administration). By identifying key recommendations from dispersed bibliography, it was possible to create a concise, standardized version for the preparation and administration of HPN, based on guidelines with the highest methodological quality.eng
dc.identifier.citationCerqueira, A., Gonçalves, D., Santos, M., & Moreira, F. (2025). Home parenteral nutrition guidelines: Review of key recommendations and proposal for standardization. 13th APLF Annual Conference, TherapeuTic advances in drug safety 16(S1), 30–31. https://journals.sagepub.com/doi/epub/10.1177/20420986251379201
dc.identifier.doi10.1177/20420986251379201
dc.identifier.eissn2042-0994
dc.identifier.issn2042-0986
dc.identifier.urihttp://hdl.handle.net/10400.22/32710
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSAGE Publications
dc.relation.hasversionhttps://journals.sagepub.com/doi/10.1177/20420986251379201
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectArtificial nutrition
dc.subjectParenteral nutrition
dc.subjectGuidelines
dc.titleHome parenteral nutrition guidelines: Review of key recommendations and proposal for standardizationeng
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferenceDate2025-10
oaire.citation.conferencePlaceAveiro
oaire.citation.endPage31
oaire.citation.issueS1
oaire.citation.startPage30
oaire.citation.title13th APLF Annual Conference - TherapeuTic advances in drug safety
oaire.citation.volume16
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameMoreira
person.givenNameFernando
person.identifier2947760
person.identifier.ciencia-id5F16-AB92-94D0
person.identifier.orcid0000-0002-3452-1459
relation.isAuthorOfPublication81213e80-09a5-4655-93dc-e54199edb2fe
relation.isAuthorOfPublication.latestForDiscovery81213e80-09a5-4655-93dc-e54199edb2fe

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