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Orientador(es)
Resumo(s)
Mitochondrial dysfunction and protein aggregation are two phenomena that have been correlated with neurodegenerative diseases and are both interlinked with cellular oxidative stress. Mitochondrial dysfunction is associated with nucleic acid damage and protein aggregation with mistakes in protein folding. However, aggregation has not yet been defined as a cause or consequence of neurodegenerative diseases.
Descrição
Palavras-chave
Neurodegenerative diseases DNA damage Protein aggregation Oxidative stress
Contexto Educativo
Citação
Allen, A., Cunha, S., Prudencio, C., & Vieira, M. (2019). Study of oxidant and anti-oxidant molecular alterations in an eukaryotic model. 4th Meeting of Medicinal Biotechnology, 42.
Editora
Escola Superior Saúde Instituto Politécnico Porto