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- Beyond low back pain! The influence of physical activity on mental health, reflected in the functionality of people with low back painPublication . Parolini, Franciele; Becker, Klaus; Goethel, Márcio; Fernandes, Ricardo J.; Fonseca, Hélder; Ervilha, Ulysses F.; Vilas-Boas, João Paulo; Santos, RubimPsychological factors play a crucial role in the experience of acute low back pain and may influence functional outcomes. However, the interplay between these factors and levels of physical activity remains poorly understood. This cross-sectional observational study examined the relationship between psychological variables and functional disability in individuals with acute low back pain, considering different levels of physical activity. Data were collected from 1021 participants through an online platform between 8 June 2022 and 8 April 2023. Standardized instruments were used to assess functional limitations, emotional distress (depression, anxiety, and stress), daily pain catastrophizing, and physical activity levels. A canonical correlation analysis was conducted to explore the multivariate associations between psychological and functional variables. There was a statistically significant association between higher levels of emotional distress and greater functional impairment related to low back pain. This association was observed in both the light-physical-activity group (canonical coefficient = 0.266; p = 0.017), the moderate-physical-activity group (0.237; p = 0.092), and the vigorous-physical-activity group (0.177; p = 0.013). Participants engaging in vigorous physical activity exhibited more favorable psychological profiles and lower functional disability compared to those with lower levels of activity. Regular and vigorous physical activity appears to be a protective factor for mental health and may help reduce functional disability in individuals with acute low back pain. These findings underscore the importance of considering physical activity levels when addressing psychological and functional outcomes in this population.
- Cochlear hair cell regeneration based on stem cells: A systematic reviewPublication . Costa, Vítor Bruno; Tomé, David; Çirtlik, Zeynep Yağmur; Öztürk, Yaren; Clemêncio, Filomena; Pitt-Byrne, Theresa; Tomé, David; Costa Clemêncio, Filomena MariaAccording to the World Health Organization (WHO), by 2050 at least 700 million people will need access to hearing care and hearing rehabilitation services. The search for cell or gene therapies has been intensifying, and stem cell therapy looks a promising candidate to support hearing regeneration and reduce these numbers. The aim of this study is to provide an overview of current advances in stem cellbased therapies for cochlear hair cell regeneration and the processes being developed for future applicability. Identification and review of all articles in the databases PubMed, Web of Science, and PLoS One using the terms stem cell, auditory hair cell regeneration, and mammalian during February 2023 and following the PRISMA guidelines. 50 articles were obtained, published between 2003 and 2022 and were systematically analyzed. The current research quantity is limited and further studies are needed, particularly in human tissue. The simultaneous use of cell therapy and gene therapy may lead to more promising results. Moreover, advances in cochlear hair cell regeneration with stem cells suggest there is a realistic potential to make the technique a useful future therapy.
- Precision and reliability of a dynamometer for trunk extension strength and steadiness assessmentPublication . Parolini, Franciele; Goethel, Márcio; Robalino, Johan; Becker, Klaus; Sousa, Manoela; Pulcineli, Barbara C.; Ervilha, Ulysses F.; Vilas-Boas, João Paulo; Santos, Rubim; Rubim Silva Santos, Manuel; Carvalho Santos Parolini, FrancieleLow back pain is a major cause of disability worldwide, often associated with deficits in trunk extensor strength control. Accurate assessment of trunk extension strength control is crucial for diagnosing impairments and monitoring interventions. This study evaluated the reliability of a dynamometry-based protocol for isometric trunk extension strength control assessment. Twenty-eight healthy volunteers (9 females, 19 males) completed two sessions, seven days apart. A single-point load cell system, encapsulated within a 3D-printed structure and connected to a Delsys system® at a sampling frequency of 2000 Hz, was used for data acquisition. Participants performed maximal voluntary contractions (MVC) and submaximal isometric contractions (SMVC) guided by trapezoidal visual feedback. Key outcome variables included peak force, mean force, and force steadiness. Calibration demonstrated high accuracy (R2 = 1) with a low root mean square error (0.55 N). Test–retest analysis showed excellent reliability for peak force (ICC = 0.81, SEM = 0.50, MDC = 1.39), mean force (ICC = 0.93, SEM = 0.17, MDC = 1.08), and steadiness (ICC = 0.87, SEM = 0.85, MDC = 2.36), with no significant intersession differences (p > 0.05). This study demonstrates the high reliability of using dynamometry to assess trunk extension strength during MVC and SMVC, endorsing the dynamometer as a tool for functional assessment and the development of personalized rehabilitation and training strategies.
- The influence of artificial breast volume induction on postural stability, postural orientation, and neuromuscular control in healthy women: a cross-sectional studyPublication . Guedes, Diana C.; Carneiro, Daniela Ferreira; Alves, Leonel Agostinho Teixeira; Melo, Ana S. C.; Moreira, Juliana; Cunha, Bruno; Santos, Rubim; Noites, Andreia; Sousa, Andreia S. P.; C. Guedes, Diana; Melo, Ana; Santos Moreira, Juliana; Cunha, Bruno; Rubim Silva Santos, Manuel; Noites, Andreia; Pinheiro de Sousa, Andreia SofiaThe percentage of breast augmentations has increased in recent years alongside the frequency of implant removals. Musculoskeletal and postural disorders are often overlooked during this removal process. Research indicates that excess anterior load from breast implants can disrupt postural control and potentially lead to short- or long-term musculoskeletal dysfunction. This study aims to evaluate the immediate changes in postural control after artificial breast augmentation in healthy female volunteers. Spinal angles, the center of pressure (CoP), and electromyographic activity of the spinal muscles were recorded in the static position and during the functional reach test (FRT) without and with implants of different volumes (220 mL, 315 mL, and 365 mL). Subjective perceptions of effort, comfort, weight, and performance in the FRT were also assessed. Statistical differences were significant in the scapular elevator during the one-minute standing position (lower activation with the 220 mL implant compared to the control and 315 mL) and in the trapezius muscles during the FRT (lower activation in the upper trapezius in the 315 mL vs. control in the reach phase and 220 mL vs. control in the return phase and higher activation in the lower trapezius in the 315 and 365 mL vs. control in the reach phase). Additionally, significant differences were identified in the performance of the FRT and the associated subjective perceptions. Breast implants with sizes of 220, 315, and 365 mL can alter scapular neuromuscular control, but these differences do not seem substantial enough to result in negative biomechanical effects in the short-term analysis.
- Spectral measurement of an arquiled arquicity R1 LED streetlight installed at Cumeada, dark sky AlquevaPublication . Lima, Raul Cerveira; Bará, SalvadorDuring late 2016 the national Portuguese electricity operator, Electricidade de Portugal (EDP), changed the streetlights of the hamlet of Cumeada, Reguengos de Monsaraz, Évora, to white light emission diodes technology (LED). The hamlet of Cumeada is within the borders of the Starlight Tourism Destination Dark Sky Alqueva (DSA). We evaluated in lab the spectrum and the CCT of one of those LED. The results revealed the LED luminaires installed in the hamlet are not appropriate for use in a dark skies reserve.
- An easy procedure for calibrating data acquisition systems using interleavingPublication . Clemêncio, Filomena; Loureiro, Custódio F. M.; Correia, Carlos M. B. A.Interleaving data acquisition channels is a well-known and interesting technique to achieve higher acquisition rates. However, to obtain the expected benefits, a careful look at the interleaving technique and to mismatches that can lead to unwanted harmonic distortion and noise is essential. In this paper we discuss the methods used to interleave existing high-speed, 250 MSPS 8-bit acquisition channels, and the results obtained. The methods presented allowed a good relative channel calibration in amplitude (amplitude mismatch under 0.1 lsb) and in time (time mismatch between acquisition channels in the ps range, under the specified maximum jitter for the ADC used). A dynamic, by software, amplitude level signal-dependent adjustment procedure is also suggested for signals with rich frequency content that can substantially improve the quality of the acquired signal when using interleaved channels. The techniques presented provide good results even in the presence of noise.
- Outdoor systems performance and upgradePublication . Lopes, L.; Andringa, S.; Assis, P.; Blanco, A.; Carolino, N.; Cerda, M.A.; Clemêncio, Filomena; Conceição, R.; Cunha, O.; Dobrigkeit, C.; Ferreira, M.; Loureiro, C.; Mendes, L.; Nogueira, J.C.; Pereira, A.; Pimenta, M.; Saraiva, J.; Sarmento, R.; Teixeira, P.; Tomé, B.Over the last two decades, the possibility of using RPCs in outdoors systems has increased considerably. Our group has participated in this effort by installing several systems and continues to work on their optimization, while simultaneously studying and developing new approaches that can use RPCs in outdoor applications. In particular, four detectors were deployed in the field at the Pierre Auger Observatory in 2019 remained inactive, awaiting the commissioning of support systems. During the pandemic the detectors were left without gas flow for more thantwo years, but were recently reactivated with no major problems. The Lou Mu project combines particle physics and geophysics in order tomapmeter-scale geologic structures, using Muon Tomography. Transmission muography is sensitive to the total amount of matter crossed by the muons, allowing to separate targets of different densities. In this exploratory project, it serves to identify unconsolidated rockzones, like geological faults and ore masses around an old Pyritemine,now converted into a science center. The general goal is to compare how effective is the muographic survey when compared with the more standard geophysical techniques. The development of the RPC system used and the data from the last two years will be presented. Finally, recent advances in a large area(1m2) doubl egap-sealed RPC will be presented.
- Quantifying the visual impact of wind farm lights on the nocturnal landscapePublication . Bará, Salvador; C. Lima, RaúlWind farm lights are a conspicuous feature in the nocturnal landscape. Their presence is a source of light pollution for residents and the environment, severely disrupting in some places the aesthetic, cultural, and scientific values of the pristine starry skies. In this work we present a simple model for quantifying the visual impact of individual wind turbine lights, based on the comparison of their brightness with the brightness of well- known night sky objects. The model includes atmospheric and visual variables, and for typical parameters it shows that medium-intensity turbine lights can be brighter than Venus up to ~4 km from the turbine, brighter than CMa (the brightest star on the nighttime sky) until about ~10 km, and reach the standard stellar visibility limit for the unaided eye (m v =+6.00) at ~38 km. These results suggest that the visual range of wind farms at nighttime may be significantly larger than at daytime, a factor that should be taken into account in environmental impact assessments.
- Acupuncture effect on reaction-time changes in Parkinson’s disease patients—Case study seriesPublication . Pereira, Catarina Ramos; Greten, Henry J.; Santos, Rubim; Reis, Ana Mafalda; Ramos, Bruno; Santos, Maria João; Machado, Jorge; Criado, Maria BegoñaParkinson’s Disease (PD) is a progressive neurodegenerative condition associated with deficit in reaction time which can lead to falls, resulting in limited independence, diminished quality of life, heightened rates of institutionalization and increased healthcare costs. We aimed to examine the effects of an acupuncture protocol in motor time response after an auditory stimulus. Methods: This study employed a case series design. Reaction time to exposed rhythmic and random auditory stimuli outcomes were evaluated at six different moments over a month-long acupuncture treatment protocol using the MP 36 system from Biopac Systems. Results: We observed a tendency to have more pronounced improvements in the time response in the more affected side of the body compared with the contralateral one. Patients tended to show better values of response to random auditory stimuli compared to rhythmic auditory ones. We also observed a tendency to obtain better results when considering the accumulative effects of the acupuncture protocol. Conclusions: Our findings indicated a possible role of reaction time as a sensitive and useful tool for motor function assessment in PD patients. Also, from our results, we concluded that the acupuncture protocol used may lead to an improvement in efficacy of motor response after aleatory and rhythmic stimulus; we also found a tendency for a higher efficacy of acupuncture in random stimuli responses in the first stages of the disease. However, further in-depth research, including a statistical evaluation with a larger participant pool, is necessary to validate and confirm these promising results.
- Antagonist coactivation of muscles of ankle and thigh in post-stroke vs. healthy subjects during sit-to-stand taskPublication . Pinho, Liliana; Sousa, Andreia S. P.; Silva, Cláudia; Cunha, Christine; Santos, Rubim; Tavares, João Manuel R. S.; Pereira, Soraia; Pinheiro, Ana Rita; Félix, José; Pinho, Francisco; Sousa, Filipa; Silva, AugustaThis study aims to analyse the coactivation of antagonist muscles of the thigh and ankle during the sit-to-stand task in post-stroke subjects, specifically during forward and antigravity sub-phases. A group of 18 healthy subjects and another with 18 subjects with a history of stroke participated voluntarily in this study. Bilateral surface electromyography (EMGs) of the soleus, gastrocnemius medialis, tibialis anterior, rectus femoris and biceps femoris muscles were collected synchronously with ground reaction forces (GRF) during the sit-to-stand task. The magnitude of electromyographic (EMG) activity was analysed during forward translation and antigravity sub-phases which were determined through GRF signals. The coactivation was calculated to quantify the degree of antagonist coactivation according to the role of the muscles during the task. Statistically significant values were found between antagonist coactivation on both sub-phases of the sit-to-stand task when comparing healthy and post-stroke subjects (healthy with ipsilesional (IPSI); healthy with contralesional (CONTRA); and healthy with IPSI and with CONTRA limbs) in all muscle pairs analysed (p < 0.01), except on thigh muscles (p > 0.05), in the antigravity sub-phase. When comparing IPSI with CONTRA sides in post-stroke subjects, no statistically significant differences were found. Increased values of antagonist coactivation were observed in post-stroke subjects compared to healthy subjects (both IPSI and CONTRA limb) in the two sub-phases analysed. The forward sub-phase CONTRA limb showed higher antagonist coactivation compared to IPSI, while in the antigravity sub-phase, IPSI antagonist coactivation was higher than in the CONTRA. In conclusion, post-stroke subjects presented an antagonist coactivation more dysfunctional at the ankle joint muscles compared to the thigh segment. So, it seems that the distal segment could express more accurately the central nervous system dysfunction in post-stroke subjects, despite the need for further studies to achieve a better spatiotemporal understanding of the variability on coactivation levels.