ESS - DM - Mestrado Europeu em Tecnologia Médica e Negócios em Saúde
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- Design proposal for wearable device to monitor psoriasis and its comorbiditiesPublication . Monzón, Roberto Alexis Rivas; Ribeiro, Maria Cristina de Castro; Guimarães, Pedro SousaPsoriasis is a common, chronic, non-infectious skin disease that has no clear cause and no definitive cure. The body produces new skin cells that rapidly accumulate on the surface of the skin, forming red papules and plaques, it can appear on any area of the body and usually covered with white or silver scales that cause itching, stinging and pain. Psoriasis can be triggered by external and internal triggers and it can affect people of any age and from any country. There is no treatment that gives hope of a complete cure for psoriasis and it is still based on symptom control. People with psoriasis have a higher risk of developing chronic degenerative diseases compared to the general population. which contribute substantially to morbidity and mortality. Until now, there is no device on the market designed to monitor comorbidities associated with psoriasis, which in the long term represent a risky situation for the patient. The use of wearable technology will be a great step in the monitoring and diagnosis of psoriasis and its comorbidities. The main objective of the present work was the development of a modular and personalized wearable device that could help in monitoring the state and evolution of the disease, registering on real time UV radiation intensity as well as the intensity and periodicity of scratching. The proposed wearable device, will work in conjunction with a mobile app to facilitate and encourage the patient to monitor himself.
- Causal discovery from time series dataPublication . Almeida, Fernanda Ribeiro de; Coelho, Luís; Fraunhofer, Vitor Rolla; Fraunhofer, Vânia GuimarãesThe drive to understand the laws that govern the universe and ourselves in order to expand our view of reality is deeply rooted in humanity. In science, this urge is a robust process filled with challenges and opportunities given the rapidly growing technology-driven volume of time series data. Causal discovery supports science in an innovative and fast-growing manner with the essential goal of uncovering mathematical orders directly from observational data translated into causal association networks. This scientific tool pledges to accelerate growth in various fields, including life sciences. This work approaches the topic of causal discovery on two levels. First, we address the theory of constraint-based methods on detecting and quantifying causal relations, covering how the methods work, the challenges they face, and the opportunities they present. Second, we explore the PCMCI method with an implementation on both synthetic and real-world data. The results of this work found in applying causal discovery in real physiological signals data may provide insights into the prospects and difficulties of causal structure search in healthcare Big Data and, moreover, the advantages of using causal models in prediction.
- Digital CT solutions for oncology applications: how to face current market and clinical challanges?Publication . Batista, Célia Catarina Rodrigues; Ventura, Sandra Rua; Wallard, Alexandre; Schmidt, Sebastian; Schmolke, SusanneLung, Liver and colorectal cancer represente greatburdens for the society nowadays and the increase of survivsl rates rely in early detection and treatment enhancement. Computed Tomography (CT) palys a major role in several steps of the clinical pathway in oncology. Artificial Intelligence and overall digital solutions for CT aim to improve medical imaging capabilities, therefore can improve cancer clinical workflows through several features and products, such as Computed Aided Detection capabilities, malignancy prediction and automatic contouring for Radiaion Therapy, among other features. Siemens Healthineers is a pioneer in CT technology, owning one of the largest digital portfolio analysis for lung, liver, and colorectal cancer, and presente somo strategies to potentiate Siemens Helthineers as a market leader regarding digital CT solutions for oncology applications. For lung cancer, T plays a major role throughout all the clinical pathway, with Siemens Helthineers offering diferente digital solutions for each step of the patient journey, however there is a high level of competion, and the clinical needs rely on automation of time-consuming tasks. Focusing on market analysis for Al-Rad Companion Chest CT, the target is broad, but the clinical value compared to competition does not stand out. Finding strategies to increase the added value of the digital CT solutions for Lung Cancer is necessary to gain market shares. Regarding liver cancer, CT plays na importante role in some steps of the clinical pathway, with Siemens Healthineers offering diferente digitl solutions for each step; the comption leve lis médium and the clinical needs rely on liver function nd tumour assessment; regarding market information, syngo. CT Liver Analysis has great added value, however a narrow targetwhich affects the final ROI. Creating solutions with broader application might increase the ROI for digital CT solutions in liver cancer. For colorectal cancer, CT Colonography (CTC) might be essential for certain patients and its role in the future might be crucial for colorectal cancer screening. Siemens Helthineers i sone of the few companies offering a digital solution for CTC, however the competiton is inexistente, and the market assessment relies on the future of CTC in the standard of care for colorectal cancer. Measurements to bring innovation and efficiency to the current complete and complex digital portfolio will allow to achieve a position of market leader in lung, liver, and colorectal CT digital market through empowerment of comercial and clinical value.
- Development of a graphical user interface for rehabilitationPublication . Oliveira, Cristina Costa; Ventura, Sandra Rua; Santos, RubimHuman movement underlies everything humans do, from movements that people can not consciously control to those movements that are trained. Everything from breathing to walking. This means movement is a very important part of human life. This was one of the main reasons to develop a whole study field around the human movement called Biomechanics. biomechanics studies the human movement from a mechanic point of view employing physics, methematics and engineering. In order words, biomechnics is very complex and needs powerfultools that allow precise analyses. Biomechanical analyses include retrieving the data froma human subject and later study it by transforming it in numbers that can be read and understood easily by the professionals in this field of study. In this dissertation, the main goal was to develop a tool (Graphical User Interface) that allowed the biomechanical analyses of three different types of movements, walking, reaching and equilibrium. This Graphical User Interface was developed with Matlab programming language, more specifically using their feature called App Designer, that allows the creation of graphical user interfaces in a simple, clear and understandable way. The tool was developed in collaboration with the Center of Rehabilitation Research from the School of health of Plytechnic of Porto and to combat their main problem when performing biomechanical analyses in the data files obtained from Optoeletronic Systems and force plates. The final product achieved was only able to perform equillibrium analyses using the center of pressure of the subject. The graphical user interface is able to calculate area, distance, velocity and maximum/minimum. the tool permits a fast, effective and accurate analysis, responding to the needs of researchers in the biomec hanical area and especially of the CIR.
- Digital skills role in radiation therapist' s profile: case studyPublication . Gonçalves, Dina Isabel Pereira; Bravo, Isabel; Barbosa, BárbaraModern radiation therapy is an intricate field, continuously facing technological progression and complexity intensification. In order to provide the best treatment possible to the patientes, it is essential that the radiation therapists have appropriate and continuous training, attending the perpetually demanding needs of the field. The digital tranformation is happening at a fast pace. It has the potential to transform and disrupt economies, industries, societies, and individuals. The digitalisation of the economu affexts grandly the labour market, increasing the demand for professionals with digital skills. Given the lack of studies on the role of digital skills in the radiation therapist's profile, this study aims to compensate for this breach, by assessing digital skills and possibel gaps in the professional profile. The study was conducted between February 2019 and august 2019. Perceptual analysis of 46 radiation therapists was included in the study. The results reveal that 84,8% of the sample has a medium level of digital skills development. Additionally, are reported that 10,9% of the assesses individuals has a high level and 4,3% presented a low level of digital skills development. Further studies are recommended, in order to identify the specific digital skills where the radiation therapists are in need of further training.