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- 11 - Collagen-like materials for tissue regeneration and repairPublication . Teixeira, Cátia; Ferraz, Ricardo; Prudêncio, Cristina; Gomes, PaulaPeptides can be designed to recreate the higher-order assembly (triple helix) and biological function of natural collagens. Collagen triple-helical domain contains Gly-Xaa-Yaa triplets where Xaa and Yaa are frequently proline and hydroxyproline, respectively. Glycine must be in every third position forming a hydrogen bond to an adjacent proline to stabilize collagen structure. Hydroxyproline residues are important in the thermal stability of the collagen triple-helix conformation. Although it is difficult to produce a stable triple helix, collagen-like peptides can be used to produce scaffolds that mimic natural tissue networks for biomedical engineering, without the liabilities of nonhuman natural collagens such us immunogenicity and pathogen transmission. This chapter describes the major approaches towards synthesis of collagen-like peptides, essentially aimed at production of artificial biocompatible and biofunctional frameworks for regenerative medicine.
- 1993Publication . Alves, Cesário
- 21st Century skills: some pedagogical approaches and reflections in a polytechnical superior schoolPublication . Braga, InêsThis analysis of the post Bologna Declaration Portuguese Higher Education System (from 2006) will highlight that despite the mandatory adjustments such has reducing the length of study cycles this system has not yet succeeded in and creating curricula that visibly reflect the development of the skill for academic and professional survival in the 21st century. Exceptions can be found and it is likely that transversal work exists within the courses. It is, however, strongly dependent on the training and awareness of its faculty, whereas the ideal setting would be that the training of such skills was in curricula. Upon conducting the literature review, the theoretical basis for this paper is anchored on Standards and on Information Science organizations’ studies on Information Literacy such as those of the American Library Association (ALA) – e.g. Information Literacy Competency Standards for Higher Education (ALA, 2000), Standards for the 21st Century Learner (ALA, 2007), Learning 4 Life: The National Plan for Implementation of Standards for the 21st Century Learner (2008). Within the context of the information society, of the constantly emerging information and communication technologies, and of the participatory culture we find the research of Henry Jenkins and co-authors - New Media Literacy White Paper. Confronting the challenges of participatory culture: media education for the 21st century (2006) and the more recent Skills for Today Research Series (P21, 2017) noteworthy. The data presented is the result of a research carried out within Porto Polytechnic in a scope comprising courses from diverse scientific areas. The data illustrates the contrast between a) the perception of teachers and students indicating that Information Literacy (IL) skills are fairly well developed within the training process and b) the results of IL tests applied to students being mostly negative. This paper reports some teaching and learning experienced by an Information Science and Communication teacher hoping it may help improving the adoption of pedagogical strategies that can motivate and potentiate a more effective development of IL skills. We believe that, in addition to an institutional involvement by management, faculty, librarians and, first and foremost, students, in this complex collaborative task of formation, these reflexions will contribute to make these individuals in the process of training more autonomous, critical, responsible, active and successful as students, workers and citizens.
- 3.2.9 Peter Pan e o tempo em que era possível voarPublication . Gomes, José AntónioPublicado em 1911, com o título Peter Pan and Wendy, o romance do tipo maravilhoso conhecido por Peter Pan, de J. M. Barrie, aborda com inegável originalidade a temática do crescimento e das suas tensões, sem no entanto abdicar de retratar a infância como uma espécie de reserva poética, irredutível à "normalização" da adultez. Obra poderosa de imaginação e de linguagem, criadora de um mito e reveladora de um profundo conhecimento da criança; obra de considerável potencial tanto do ponto de vista puramente dramático como no plano da virtualidade cinematográfica (daí as várias adaptações e recriações que ajudaram a imortalizá-la, transpondo-a para a cultura de massas), Peter Pan reuniu diversas condições para rapidamente se tornar um clássico. A elas se deve juntar a circunstância de ter sido traduzido e, como tal, difundido em numerosas línguas.
- 3D Vocal Tract Reconstruction Using Magnetic Resonance Imaging Data to Study Fricative Consonant ProductionPublication . Ventura, Sandra Moreira Rua; Freitas, Diamantino Rui S.; Ramos, Isabel Maria A. P.; Tavares, João Manuel R. S.The development of Magnetic Resonance Imaging (MRI) has grown rapidly in clinical practice. Currently, the use of MRI in speech research provides useful and accurate qualitative and quantitative data of speech articulation. The aim of this work was to describe an effective method to extract vocal tract and compute their volumes during speech production from MRI images. Using a 3.0 Tesla MRI system, 2D and 3D images of the vocal tract were collected and used to analyze the vocal tract during the production of fricative consonants. These images were also used to build the associated 3D models and compute their volumes. This approach showed that, in general, the volumes measured for the voiceless consonants are smaller than the counterpart voiced consonants.
- À Clara e aos pássaros de ferroPublication . Ferreira, Ângela
- Acoustic Emission Studies in Hip Arthroplasty – Peak Stress Impact In Vitro Cemented ProsthesisPublication . Gueiral, Nuno; Nogueira, ElisabeteEngineering has a very important role in the development of non-destructive monitoring of orthopaedical systems allowing the evaluation of its integrity. Sir John Charnley revolutionized the field of joint arthroplasty in the 1960s with the development of the total hip replacement. He replaced the diseased hip joint with a steel femoral component and a plastic acetabular socket cup combination, both fixed into the bone using a self-curing acrylic cement, polymethylmethacrylate (PMMA) (Browne et al, 2005). That way, he has restored some of the most problematic joints in the human body. The placement of the metal implant in the channel open in the femoral bone without using cement or by mechanical attack, called a non cemented arthroplasty, came into use in an effort to solve the problem.
- Acquisition of higher-order experimental skills through remote and virtual laboratoriesPublication . Restivo, Maria Teresa; Alves, Gustavo R.Remote laboratories are physical spaces with real apparatus and real instruments connected to the Internet. They allow both students and teachers to remotely conduct real experiments through a simple web browser.
- Active Learning Strategies for Sustainable Engineering: The case of the European Project Semester at ISEPPublication . Duarte, Abel J.; Malheiro, Benedita; Silva, Manuel F.; Ferreira, Paulo; Guedes, PedroEngineering aims to improve the quality of daily life on a planet with limited resources. This chapter describes how the European Project Semester offered by the School of Engineering of the Porto Polytechnic contributes to make engineering undergraduates conscious of their environmental and societal impact. The program is a project-based active learning framework where problem-solving is supported by intercultural communication and creativity, ethical and sustainable reasoning, and global contextual analysis. This analysis shows that it fosters scientific, technical, and interpersonal competencies, emphasizing ethical and sustainable design as recommended by several reference institutions through the testimonials left on the project reports and the evolution perceived by the participants during the semester. These findings are supported by a sample of 45 projects conducted by 228 students from 23 countries and 65 degrees. All projects aimed to have a lasting impact on the future engineering practice of participants and, somehow, transform the world positively.
- Active lifestyle in schizophrenia: How to combine exercise and therapy in practice?Publication . Simões de Almeida, Raquel; Marques, AntónioSchizophrenia is a mental illness with intense effects on a person’s life. In addition to the psychiatric symptoms, patients with schizophrenia generally have multiple somatic comorbidities, such as cardiovascular and metabolic disorders. High prevalence of an unhealthy lifestyle (smoking habits, poor diets, sedentarism) contributes to the increased risk in these patients. Even though schizophrenia treatment focuses on medication in conjunction with talking therapies, it is essential to address lifestyle choices. Nowadays there is a large body of evidence that suggests that physical activity and exercise can help improve not only schizophrenia patients’ physical health but also their mental and psychological wellbeing. This chapter addresses the guidelines for physical activity and exercise interventions for schizophrenia, presenting some programs which combine exercise and therapies to treat schizophrenia, including some novel digital approaches. This chapter also gives some recommendations for an active lifestyle clinical integration providing a literature review on the subject.