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Pain intensity (PI) and quality of life (QoL) in patients with chronic non-cancer pain (CNCP) receiving medication review –A protocol

dc.contributor.authorDuarte, Nuno
dc.contributor.authorSantos, Marlene
dc.contributor.authorPedraza, José
dc.date.accessioned2024-07-15T14:16:49Z
dc.date.available2024-07-15T14:16:49Z
dc.date.issued2023-12-04
dc.description.abstractChronic pain is defined by the International Association for the Study of Pain (IASP) as “pain that lasts or occurs for longer than 3 months”.A recent prevalence study conducted in primary care units in Portugal found a 33,6% prevalence of chronic pain. The study highlights a high prevalence of chronic pain patients while also identifying some characteristics and associated risk factors. In medication review with follow-up (MRF), care plans are developed with the patient’s agreement and recommendations regarding pharmacotherapy changes are discussed with physicians to optimize clinical outcomes. Implementation of MRF in chronic non-cancer pain (CNCP) patients in primary care setting, and compare this intervention with standard care by assessing, its influence on pain intensity (PI), quality of life (QoL) and patient global impression (PGI). A randomized parallel study, with blinding to patients relative to interventions and blinding to assessment, consisting of two arms, the intervention where MRF will be conducted, and the “active placebo” which will comprise standard care. Outcomes are assessed by self-report using a numerical rating scale (NRS) for PI, the brief pain inventory for QoL and patient global impression of change scale for PGI (secondary outcome). A PI improvement of 1,5 points in the NRS between-groups on average PI score from baseline until the end of the study, is defined as the minimal clinically relevant difference (MCRD). Standard deviation (SD) estimate was obtained based on interquartile range of a prevalence study on chronic pain in Portugal which gives an SD of 1,48. To detect the MCRD and considering the SD estimate, a confidence interval of 95% and a power size to detect effect of 80%, the sample size must be approximately 15 subjects for each arm (n=30) for a two-sided test. We hypothesized that these main outcomes will be different between groups, favoring the group receiving MRF.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDuarte, N., Santos, M., & Pedraza, J. (2023). Pain intensity (PI) and quality of life (QoL) in patients with chronic non-cancer pain (CNCP) receiving medication review – A protocol. Proceedings of Research and Practice in Allied and Environmental Health - 11º Congresso Nacional da APLF, 1 (3), 10. https://doi.org/10.26537/prpaeh.v1i3.5352pt_PT
dc.identifier.doi10.26537/prpaeh.v1i3.5352pt_PT
dc.identifier.issn2975-9420
dc.identifier.urihttp://hdl.handle.net/10400.22/25786
dc.language.isoengpt_PT
dc.publisherCentro de Investigação em Saúde e Ambiente, Escola Superior de Saúde, Instituto Politécnico do Portopt_PT
dc.relation.publisherversionhttps://parc.ipp.pt/index.php/PRPAEH/article/view/5352pt_PT
dc.subjectChronic painpt_PT
dc.subjectMedication reviewpt_PT
dc.subjectProtocolpt_PT
dc.subjectRandomized studypt_PT
dc.titlePain intensity (PI) and quality of life (QoL) in patients with chronic non-cancer pain (CNCP) receiving medication review –A protocolpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePortopt_PT
oaire.citation.endPage10pt_PT
oaire.citation.startPage10pt_PT
oaire.citation.titleProceedings of Research and Practice in Allied and Environmental Health - 11º Congresso Nacional da APLFpt_PT
oaire.citation.volume1 (3)pt_PT
person.familyNameDuarte
person.familyNameSantos
person.givenNameNuno
person.givenNameMarlene
person.identifier1508370
person.identifier.ciencia-id311A-335C-3FCE
person.identifier.ciencia-id8311-B967-31C4
person.identifier.orcid0000-0002-9690-0374
person.identifier.orcid0000-0001-5020-5942
person.identifier.scopus-author-id57110502000
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublication7277d917-5b9c-4143-8d6f-8dc02bc71155
relation.isAuthorOfPublication8ce9ee39-a4c6-46ae-99e2-49397b550f1b
relation.isAuthorOfPublication.latestForDiscovery7277d917-5b9c-4143-8d6f-8dc02bc71155

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