Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism

Caldevilla, Renato; Santos, Marlene; Barroso, M. Fátima

http://hdl.handle.net/10400.22/25755

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Authors

Caldevilla, Renato

Santos, Marlene

Barroso, M. Fátima

Abstract(s)

Major depression disorder (MDD) is the most prevalent psychiatric condition worldwide. Currently, antidepressants constitute the main pharmacological treatment for this condition. Despite the growing arsenal of antidepressant medications, almost half of MDD patients have insufficient remission rates during their treatments. A growing body of scientific evidence points to genetic factors as having a crucial role in patients’ response to antidepressant treatments. One of these genetic components is the BDNF gene, that codes for the BDNF neurotrophin, an important player in neuroplasticity and neurogenesis.

Keywords

Major depression disorder BDNF gene

URI

http://hdl.handle.net/10400.22/25755

Citation

Caldevilla, R., Santos, M., & Barroso, M. F. (2023). Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism. Em R. P. Rocha & J. L. Faria (Eds.), Livro de Resumos do XXVII Encontro Luso-Galego de Química (p. 282). Sociedade Portuguesa de Química.