Repository logo
 
Publication

Stalling the course of neurodegenerative diseases: could cyanobacteria constitute a new approach toward therapy?

2023-09Journal article Open access
Simple item page
dc.contributor.authorRamos, Vitória
dc.contributor.authorReis, Mariana
dc.contributor.authorFerreira, Leonor
dc.contributor.authorSilva, Ana Margarida
dc.contributor.authorFerraz, Ricardo
dc.contributor.authorVieira, Mónica
dc.contributor.authorVasconcelos, Vitor
dc.contributor.authorMartins, Rosário
dc.date.accessioned2023-10-02T13:52:50Z
dc.date.available2023-10-02T13:52:50Z
dc.date.issued2023-09
dc.description.abstractNeurodegenerative diseases (NDs) are characterized by progressive and irreversible neuronal loss, accompanied by a range of pathological pathways, including aberrant protein aggregation, altered energy metabolism, excitotoxicity, inflammation, and oxidative stress. Some of the most common NDs include Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Multiple Sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), and Huntington’s Disease (HD). There are currently no available cures; there are only therapeutic approaches that ameliorate the progression of symptoms, which makes the search for new drugs and therapeutic targets a constant battle. Cyanobacteria are ancient prokaryotic oxygenic phototrophs whose long evolutionary history has resulted in the production of a plethora of biomedically relevant compounds with anti-inflammatory, antioxidant, immunomodulatory, and neuroprotective properties, that can be valuable in this field. This review summarizes the major NDs and their pathophysiology, with a focus on the anti-neurodegenerative properties of cyanobacterial compounds and their main effects.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRamos, V., Reis, M., Ferreira, L., Silva, A. M., Ferraz, R., Vieira, M., Vasconcelos, V., & Martins, R. (2023). Stalling the Course of Neurodegenerative Diseases: Could Cyanobacteria Constitute a New Approach toward Therapy? Biomolecules, 13(10), Artigo 10. https://doi.org/10.3390/biom13101444pt_PT
dc.identifier.doi10.3390/biom13101444pt_PT
dc.identifier.eissn2218-273X
dc.identifier.urihttp://hdl.handle.net/10400.22/23631
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2218-273X/13/10/1444pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCyanobacteriapt_PT
dc.subjectSpirulinapt_PT
dc.subjectNeurodegenerative diseasespt_PT
dc.subjectNatural productspt_PT
dc.titleStalling the course of neurodegenerative diseases: could cyanobacteria constitute a new approach toward therapy?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage34pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleBiomoleculespt_PT
oaire.citation.volume13 (10)pt_PT
person.familyNameFerraz
person.familyNameVieira
person.familyNameMartins
person.givenNameRicardo
person.givenNameMónica
person.givenNameRosario
person.identifier.ciencia-id001E-71CE-F92D
person.identifier.ciencia-idA919-DB40-EF10
person.identifier.orcid0000-0002-1761-117X
person.identifier.orcid0000-0002-9614-9031
person.identifier.orcid0000-0002-9882-4651
person.identifier.ridG-5639-2011
person.identifier.ridD-8977-2016
person.identifier.scopus-author-id24464208500
person.identifier.scopus-author-id24464652500
person.identifier.scopus-author-id21834368700
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationa5a8faa7-12a5-4b1c-bced-44c895677397
relation.isAuthorOfPublication55587c4b-3df0-4ff1-bade-587420940ecd
relation.isAuthorOfPublication82a7c349-c88e-450f-adc7-3331d69149cf
relation.isAuthorOfPublication.latestForDiscoverya5a8faa7-12a5-4b1c-bced-44c895677397

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ART_Rosário Martins.pdf
Size:
1.8 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESS - CM - Artigos
ESS - CQB - Artigos
ESS - TBIO - Artigos