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Antimicrobial activity of quinoxaline 1,4-dioxide and three derivatives

2014Conference object Open access
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dc.contributor.authorVieira, Mónica
dc.contributor.authorFernandes, Rúben
dc.contributor.authorNoronha, João Paulo
dc.contributor.authorSilva, M.
dc.contributor.authorPrudêncio, Cristina
dc.date.accessioned2013-04-19T09:16:39Z
dc.date.available2013-04-19T09:16:39Z
dc.date.issued2014
dc.description.abstractO presente trabalho descreve o estudo da actividad e antimicrobiana de quarto derivados da quinoxalina N,N-dióxido: quinoxalina 1,4-dióxido, 2-metilquinoxalina 1,4- dióxido, 6-cloro-2,3-dimetilquinoxalina 1,4-dióxido e 3-benzoil-2-metilquinoxalina 1,4- dióxido contra as estirpes bacterianas Geobacillus stearothermophilus ATCC 10149, Escherichia coli ATCC 25922, Escherichia coli HB101, Escherichia coli (blaTEM, blaCTX-M) e Salmonella (blaCTX-M), assim como contra a estirpe de levedura Saccharomyces cerevisiae PYCC 4072. A determinação da concentração mínima inibitória (MIC) foi realizada pelo método de diluição. Os valores de MIC’s foram estimados para cada composto e estirpe. Os resultados obtidos sugerem potenciais novas drogas para quimioterapia.por
dc.description.abstractThe present work reports the study of the antimicrobial activity of four quinoxaline N,N-dioxide: quinoxaline 1,4-dioxide, 2-methylquinoxaline 1,4-dioxide, 6- chloro-2,3-dimethylquinoxaline 1,4-dioxide and 3-benzoyl-2-methylquinoxaline 1,4- dioxide against Geobacillus stearothermophilus ATCC 10149, Escherichia coli ATCC 25922, Escherichia coli HB101, Escherichia coli (blaTEM, blaCTX-M) and Salmonella (blaCTX-M) bacterial strains and also against the yeast Saccharomyces cerevisiae PYCC 4072. The determination of the minimal inhibitory concentration (MIC) was performed by the dilution method. The MIC values were estimated for each compound and each microorganism. The results obtained suggest potential new drugs for antimicrobial chemotherapy.por
dc.identifier.isbn9789728688691
dc.identifier.urihttp://hdl.handle.net/10400.22/1407
dc.language.isoporpor
dc.peerreviewedyespor
dc.publisherInstituto Politécnico do Porto. Escola Superior de Tecnologia da Saúde do Porto - Politemapor
dc.subjectQuinoxaline 1,4-dioxidespor
dc.subjectAntimicrobial activitypor
dc.subjectInhibitory concentrationspor
dc.titleAntimicrobial activity of quinoxaline 1,4-dioxide and three derivativespor
dc.typeconference object
dspace.entity.typePublication
person.familyNameVieira
person.familyNameFernandes
person.familyNamePrudêncio
person.givenNameMónica
person.givenNameRúben
person.givenNameCristina
person.identifier635792
person.identifier1200571
person.identifier.ciencia-id0D1F-4090-E82A
person.identifier.ciencia-idC81E-F4EE-FADE
person.identifier.orcid0000-0002-9614-9031
person.identifier.orcid0000-0001-8933-3984
person.identifier.orcid0000-0002-9920-936X
person.identifier.ridD-8977-2016
person.identifier.scopus-author-id24464652500
person.identifier.scopus-author-id57640135700
person.identifier.scopus-author-id6508057930
rcaap.rightsopenAccesspor
rcaap.typeconferenceObject
relation.isAuthorOfPublication55587c4b-3df0-4ff1-bade-587420940ecd
relation.isAuthorOfPublication9e6c397c-62d8-4a40-8ec7-ad05ae0ebcc4
relation.isAuthorOfPublication881a8ad5-ab13-4e49-89f4-08ca61cc81e3
relation.isAuthorOfPublication.latestForDiscovery55587c4b-3df0-4ff1-bade-587420940ecd

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