Repository logo
 
Publication

Association between elevated iodine intake and IQ among school children in Portugal

2022-10-26Journal article Open access
Simple item page
dc.contributor.authorCarvalho, Irene P.
dc.contributor.authorPeixoto, Bruno
dc.contributor.authorCaldas, José Carlos
dc.contributor.authorCosta, Ana
dc.contributor.authorSilva, Sofia
dc.contributor.authorMoreira, Bárbara
dc.contributor.authorAlmeida, Agostinho
dc.contributor.authorMoreira-Rosário, André
dc.contributor.authorGuerra, António
dc.contributor.authorDelerue-Matos, Cristina
dc.contributor.authorSintra, Diana
dc.contributor.authorPestana, Diogo
dc.contributor.authorPinto, Edgar
dc.contributor.authorMendes, Francisca Castro
dc.contributor.authorMartins, Inês
dc.contributor.authorLeite, João Costa
dc.contributor.authorFontoura, Manuel
dc.contributor.authorMaia, Maria Luz
dc.contributor.authorQueirós, Pedro
dc.contributor.authorMoreira, Roxana
dc.contributor.authorLeal, Sandra
dc.contributor.authorNorberto, Sónia
dc.contributor.authorCosta, Vera
dc.contributor.authorFernandes, Virgínia Cruz
dc.contributor.authorKeating, Elisa
dc.contributor.authorAzevedo, Luís
dc.contributor.authorCalhau, Conceição
dc.date.accessioned2023-01-17T14:57:55Z
dc.date.available2023-01-17T14:57:55Z
dc.date.issued2022-10-26
dc.description.abstractThe goal of this work was to examine whether elevated iodine intake was associated with adverse effects on IQ among school-age children in Portugal. In a representative sample of children from the north of the country, IQ percentiles by age (assessed with Raven’s Colored Progressive Matrices) were dichotomized to <50 (“below-average” IQs) and ≥50. Morning urine iodine concentrations, corrected for creatinine, were dichotomized to <250 µg/g and ≥250 µg/g, according to the European Commission/Scientific Committee on Food’s tolerable upper level of daily iodine intake for young children. Data were examined with Chi-square tests, logistic regression, and GLM univariate analysis. The sample (N = 1965) was classified as generally iodine-adequate (median urinary iodine concentration = 129 µg/L; median iodine-to-creatinine ratio = 126 µg/g) according to the WHO’s criteria. A greater proportion of children in the ≥250 µg/g group had below-average IQs, compared to children with less than 250 µg/g (p = 0.037), despite a sizable (though non-significant) proportion of children in the less-than-250 µg/g group also presenting below-average IQs, at the bottom of the iodine distribution (<50 µg/g). The proportion of below-average IQs increased withncreasingly elevated iodine concentrations (p = .047). The association remained significant after the adjustment for confounders, with the elevated iodine group showing increased odds of having below-average IQs when compared with the non-elevated iodine group (OR 1.55; 95% CI 1.11–2.17; p = 0.011). Consistently, the former group presented a lower mean IQ than the latter (p = 0.006). High iodine intake was associated with lower IQs even in a population classified as iodine-adequate. These results bear on child cognition and on initiatives involving iodine supplementation.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCarvalho, I. P., Peixoto, B., Caldas, J. C., Costa, A., Silva, S., Moreira, B., Almeida, A., Moreira-Rosário, A., Guerra, A., Delerue-Matos, C., Sintra, D., Pestana, D., Pinto, E., Mendes, F. C., Martins, I., Leite, J. C., Fontoura, M., Maia, M. L., Queirós, P., … Calhau, C. (2022). Association between Elevated Iodine Intake and IQ among School Children in Portugal. Nutrients, 14(21), 4493. https://doi.org/10.3390/nu14214493pt_PT
dc.identifier.doi10.3390/nu14214493pt_PT
dc.identifier.eissn2072-6643
dc.identifier.urihttp://hdl.handle.net/10400.22/21606
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/14/21/4493pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectExcessive iodinept_PT
dc.subjectCognitionpt_PT
dc.subjectSchool agespt_PT
dc.subjectIodine-adequate populationpt_PT
dc.subjectRepresentative samplept_PT
dc.titleAssociation between elevated iodine intake and IQ among school children in Portugalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage11pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleNutrientspt_PT
oaire.citation.volume14pt_PT
person.familyNamePinto
person.givenNameEdgar
person.identifier.ciencia-id271F-B7DF-8FAB
person.identifier.orcid0000-0002-8021-4783
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationeaf9fc86-1a1c-437f-adee-d28040aa7f2f
relation.isAuthorOfPublication.latestForDiscoveryeaf9fc86-1a1c-437f-adee-d28040aa7f2f

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Art Edgar Pinto 9.pdf
Size:
335.91 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

ESS - SA - Artigos