Publication
Quantum dot-based optical sensor for MMP7 biomarker with molecularly imprinted polymers
| dc.contributor.author | Oliveira, Pedro | |
| dc.contributor.author | Piloto, Ana Margarida L. | |
| dc.date.accessioned | 2024-11-08T15:37:52Z | |
| dc.date.available | 2024-11-08T15:37:52Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | MMP7, also known as matrix metalloproteinase 7, is a biomarker for oncogenic activity in a variety of tumour types. As part of the zinc-dependent endopeptidases group, it can break down practically all protein components found in the extracellular matrix1. CdTe MPA-Capped Quantum Dots (CdTe@MPA QDs) are luminescent nanoparticles with exceptional optical features as customized particle sizes and narrow emission spectra. They can be integrated into sensing systems for the sensitive and selective detection of metal ions, biomarkers, and antibiotics2. QDs can be functionalized by in situ polymerization, which combines monomers, crosslinkers, and proteins to create recognition cavities. Upon rebinding with the target biomarker, these cavities demonstrate biomimetic recognition sites complementary to the target biomolecule. The presence of the target leads to fluorescence quenching, of the functionalized QDs with MIPs, thus allowing for a simple and straightforward method for the selective quantification of the biomolecule. | pt_PT |
| dc.description.version | N/A | pt_PT |
| dc.identifier.citation | Oliveira, P., & Piloto, A.M.L. (2024, May 23-24). Quantum dot-based optical sensor for MMP7 biomarker with molecularly imprinted polymers [Poster presentation]. VII iBiMED Symposium: Sharing science, inspiring progress, University of Aveiro, Aveiro, Portugal. | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.22/26369 | |
| dc.language.iso | eng | pt_PT |
| dc.relation | Novos sitemas óticos biomiméticos para o seguimento de biomarcadores de cancro | |
| dc.relation | Center for Innovation in Industrial Engineering and Technology | |
| dc.relation | Center for Innovation in Industrial Engineering and Technology | |
| dc.subject | MMP7 biomarker | pt_PT |
| dc.subject | Sensors | pt_PT |
| dc.title | Quantum dot-based optical sensor for MMP7 biomarker with molecularly imprinted polymers | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.awardTitle | Novos sitemas óticos biomiméticos para o seguimento de biomarcadores de cancro | |
| oaire.awardTitle | Center for Innovation in Industrial Engineering and Technology | |
| oaire.awardTitle | Center for Innovation in Industrial Engineering and Technology | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/Concurso de Projetos de I&D em Todos os Domínios Científicos - 2022/2022.07897.PTDC/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04730%2F2020/PT | |
| oaire.citation.conferencePlace | University of Aveiro, Aveiro, Portugal | pt_PT |
| oaire.citation.title | VII iBiMED Symposium: Sharing science, inspiring progress | pt_PT |
| oaire.fundingStream | Concurso de Projetos de I&D em Todos os Domínios Científicos - 2022 | |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| oaire.fundingStream | 6817 - DCRRNI ID | |
| person.familyName | L. Piloto Cerqueira | |
| person.givenName | Ana Margarida | |
| person.identifier.ciencia-id | AD1C-28E2-F781 | |
| person.identifier.orcid | 0000-0002-2374-2467 | |
| person.identifier.rid | G-5788-2018 | |
| person.identifier.scopus-author-id | 8527885100 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
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