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The impact of a rectal spacer in VMAT Dosimetry in the treatment of Prostate Cancer
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Orientador(es)
Resumo(s)
Although the dosimetric advantages of rectal spacers in prostate cancer radiotherapy have been demonstrated in selected clinical trials, real-world data from routine clinical practice remain limited—particularly within the Portuguese healthcare system. This study offers a detailed dosimetric comparison of Volumetric Modulated Arc Therapy (VMAT), with and without rectal spacer use, in a real-world patient cohort, aiming to assess the clinical relevance of spacer insertion under standard treatment protocols. A retrospective dosimetric evaluation was performed on 80 prostate cancer patients treated at a radiotherapy centre in southern Portugal. Patients were equally divided into two matched groups (n = 40): one receiving VMAT alone, the other receiving VMAT with hydrogel rectal spacer placement. Dose-volume histograms (DVHs) were analysed for the planning target volume (PTV) and key organs at risk (OARs). Standard dosimetric metrics, such as V50–V75 for the rectum and bladder, V50 for femoral heads, and mean dose for the penile bulb, were assessed. PTV coverage was evaluated using conformity and homogeneity indices. Spacer use significantly decreased rectal dose exposure across all evaluated parameters without compromising PTV coverage or increasing dose to other OARs. These findings support routine rectal spacer applications to enhance treatment safety and patient outcomes.
Descrição
Palavras-chave
Organs at risk Prostate cancer Rectal spacer VMAT Clinical dosimetry Radiotherapy
Contexto Educativo
Citação
Oliveira, S., Fernandes, R., Baylina, P., Santos, J., Vieira, G., Faria, I., & Pereira, N. (2025). The Impact of a Rectal Spacer in VMAT Dosimetry in the Treatment of Prostate Cancer. Applied Sciences, 15(17), 9414. https://doi.org/10.3390/app15179414
Editora
MDPI