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Screening the toxicity of selected personal care products using embryo bioassays: 4-MBC, propylparaben and triclocarban

2016Journal article Open access
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dc.contributor.authorTorres, Tiago
dc.contributor.authorCunha, Isabel
dc.contributor.authorMartins, Rosario
dc.contributor.authorSantos, Miguel
dc.date.accessioned2017-01-16T10:51:03Z
dc.date.available2017-01-16T10:51:03Z
dc.date.issued2016
dc.description.abstractRecently, several emerging pollutants, including Personal Care Products (PCPs), have been detected in aquatic ecosystems, in the ng/L or µg/L range. Available toxicological data is limited, and, for certain PCPs, evidence indicates a potential risk for the environment. Hence, there is an urgent need to gather ecotoxicological data on PCPs as a proxy to improve risk assessment. Here, the toxicity of three different PCPs (4-Methylbenzylidene Camphor (4-MBC), propylparaben and triclocarban) was tested using embryo bioassays with Danio rerio (zebrafish) and Paracentrotus lividus (sea urchin). The No Observed Effect Concentration (NOEC) for triclocarban was 0.256 µg/L for sea urchin and 100 µg/L for zebrafish, whereas NOEC for 4-MBC was 0.32 µg/L for sea urchin and 50 µg/L for zebrafish. Both PCPs impacted embryo development at environmentally relevant concentrations. In comparison with triclocarban and 4-MBC, propylparaben was less toxic for both sea urchin (NOEC = 160 µg/L) and zebrafish (NOEC = 1000 µg/L). Overall, this study further demonstrates the sensitivity of embryo bioassays as a high-throughput approach for testing the toxicity of emerging pollutants.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTorres, T., Cunha, I., Martins, R., & Santos, M. M. (2016). Screening the Toxicity of Selected Personal Care Products Using Embryo Bioassays: 4-MBC, Propylparaben and Triclocarban. International Journal of Molecular Sciences, 17(10), Artigo 10. https://doi.org/10.3390/ijms17101762
dc.identifier.doi10.3390/ijms17101762pt_PT
dc.identifier.issn1422-0067
dc.identifier.urihttp://hdl.handle.net/10400.22/9268
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPI Open Access Journalspt_PT
dc.relation.publisherversionhttp://www.mdpi.com/1422-0067/17/10/1762/htmpt_PT
dc.subjectPersonal care productspt_PT
dc.subjectSea urchinpt_PT
dc.subjectZebrafishpt_PT
dc.subjectEmbryo bioassayspt_PT
dc.subjectRisk assessmentpt_PT
dc.subject4-Methylbenzylidene Camphorpt_PT
dc.subjectPropylparabenpt_PT
dc.subjectTriclocarbanpt_PT
dc.titleScreening the toxicity of selected personal care products using embryo bioassays: 4-MBC, propylparaben and triclocarbanpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue10pt_PT
oaire.citation.startPage1762pt_PT
oaire.citation.titleInternational Journal of Molecular Sciencespt_PT
oaire.citation.volume17pt_PT
person.familyNameMartins
person.givenNameRosario
person.identifier.ciencia-idA919-DB40-EF10
person.identifier.orcid0000-0002-9882-4651
person.identifier.scopus-author-id21834368700
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication82a7c349-c88e-450f-adc7-3331d69149cf
relation.isAuthorOfPublication.latestForDiscovery82a7c349-c88e-450f-adc7-3331d69149cf

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