Obesity and brain cancer: proteomic analyzes of the influence of the adipocyte secretome on glioma Gl261 cells

Fernandes, Rúben; Costa, J.; Almeida, Joana; Coelho, Pedro; Cea, V.; Galésio, M.; Diniz, MS.; Prudêncio, Cristina; Sala, C.

http://hdl.handle.net/10400.22/19025

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Abstract(s)

Glioma is the most frequent form of malignant brain tumor in the adults and childhood. There is a global tendency toward a higher incidence of gliomas in highly developed and industrialized countries. Simultaneously obesity is reaching epidemic proportions in such developed countries. It has been highly accepted that obesity may play an important role in the biology of several types of cancer. We have developed an in vitro method for the understanding of the influence of obesity on glioma mouse cells (Gl261).

Keywords

Glioma Cancer Adipose tissue Obesity 2D Proteomics Mass spectroscopy

URI

http://hdl.handle.net/10400.22/19025

Citation

Fernandes, R., Costa, J., Almeida, J., Coelho, P., Cea, V., Galésio, M., Diniz, M., Prudêncio, C., & Sala, C. (2013). Obesity and brain cancer: proteomic analyzes of the influence of the adipocyte secretome on glioma Gl261 cells. 17.º Congresso Português de Obesidade - Da Patogénese à Prevenção da Obesidade.