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Development of an immunosensor based on quantum dots with different emissions for the detection of cancer biomarkers

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dc.contributor.authorOliveira, Daniela
dc.contributor.authorPiloto, Ana Margarida L.
dc.date.accessioned2024-11-11T11:46:20Z
dc.date.available2024-11-11T11:46:20Z
dc.date.issued2024
dc.description.abstract(Introduction) Cancer is a global health challenge, where early detection is crucial to increasing survival rates [1]. Non-invasive, rapid, and affordable diagnostic methods are urgently needed. Immunosensors emerge as promising alternatives to traditional methods such as ELISA, allowing point-of-care (PoC) analyses [2]. This study introduces a fluorescent probe using cadmium telluride quantum dots (CdTe@MPA QDs) to detect the pancreatic cancer biomarker CA 19-9. With the increasing CA 19-9 concentrations, the fluorescence intensity of green-, orange-, and red-emitting QDs@conjugates was reduced, creating a visible colour gradient under a 365 nm UV lamp. The method, suitable for serum analysis, is highly sensitive and selective, with a detection range of 0.31 to 501.9 U mL-1 and analyzed using ImageJ software. These immunosensors offer significant potential for cancer biomarker detection in clinical diagnostics.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.citationOliveira, D., & Piloto, A.M.L. (2024, Jun. 23-26). Development of an immunosensor based on quantum dots with different emissions for the detection of cancer biomarkers [Poster presentation]. RICI X - 10th Iberian Meeting on Colloids and Interfaces, Coimbra, Portugalpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/26377
dc.language.isoengpt_PT
dc.relationNovos sitemas óticos biomiméticos para o seguimento de biomarcadores de cancro
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.relationCenter for Innovation in Industrial Engineering and Technology
dc.subjectDiagnosis methods of cancerpt_PT
dc.subjectImmunosensorspt_PT
dc.subjectQuantum dotspt_PT
dc.subjectCancer biomarkerspt_PT
dc.titleDevelopment of an immunosensor based on quantum dots with different emissions for the detection of cancer biomarkerspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardTitleNovos sitemas óticos biomiméticos para o seguimento de biomarcadores de cancro
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardTitleCenter for Innovation in Industrial Engineering and Technology
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/Concurso de Projetos de I&D em Todos os Domínios Científicos - 2022/2022.07897.PTDC/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04730%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04730%2F2020/PT
oaire.citation.conferencePlaceCoimbra, Portugalpt_PT
oaire.citation.titleRICI X - 10th Iberian Meeting on Colloids and Interfacespt_PT
oaire.fundingStreamConcurso de Projetos de I&D em Todos os Domínios Científicos - 2022
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameDOS SANTOS OLIVEIRA
person.familyNameL. Piloto Cerqueira
person.givenNameDANIELA
person.givenNameAna Margarida
person.identifier.ciencia-idD319-DEC9-9B9F
person.identifier.ciencia-idAD1C-28E2-F781
person.identifier.orcid0000-0001-7159-2638
person.identifier.orcid0000-0002-2374-2467
person.identifier.ridG-5788-2018
person.identifier.scopus-author-id8527885100
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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