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Toxicity testing of simvastatin, sertraline, 4-MBC propylparaben and triclocarban using zebrafish and sea urchin embryos bioassays

dc.contributor.authorTorres, Tiago
dc.contributor.authorRibeiro, Sílvia
dc.contributor.authorCunha, Isabel
dc.contributor.authorMartins, Rosário
dc.contributor.authorSantos, Miguel Machado
dc.date.accessioned2024-09-19T09:08:42Z
dc.date.available2024-09-19T09:08:42Z
dc.date.issued2014-09
dc.description.abstractIn the past decade, many emergent compounds, including some active substances and ingredients of Pharmaceuticals and Personal Care Products (PPCPs) have been detected in water at levels that can negatively impact aquatic ecosystems (Lapworth et al., 2012; Jiang et al., 2013). The recent knowledge of their occurrence has raised concerns about human health effects and ecosystem risks. Although these compounds are frequently detected at concentrations that are not likely to induce adverse effects in humans and may be too low to cause acute effects in other organisms, there is still a serious lack of information about the effects in non-target species, particularly considering chronic exposure or effects resulting from interactions between them (Lapworth et al., 2012). Pharmaceuticals and Personal Care Products enter the aquatic environment from different point and nonpoint sources and wastewater treatments plants cannot ensure complete removal of many compounds, and therefore they may be present at significant concentrations in effluents (Jiang et al., 2013). Hence, it is essential to understand the effects of these substances on aquatic organisms. Owing to the large number of new chemicals that must go through toxicity testing, short-term early-life-stages have been frequently used as an alternative to long-term exposures due to its high sensitivity and logistic advantages.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTorres, T., Ribeiro, S., Cunha, I., Martins, R., & Santos, M. M. (2014). Toxicity testing of simvastatin, sertraline, 4-MBC propylparaben and triclocarban using zebrafish and sea urchin embryos bioassays. ICEH14 /3rd International Congress of Environmental Health: Proceedings Book, 1, 271–272.pt_PT
dc.identifier.isbn978-989-20-5086-7
dc.identifier.urihttp://hdl.handle.net/10400.22/26050
dc.language.isoengpt_PT
dc.publisherÁrea Científica da Escola Superior de Tecnologia da Saúde do Instituto Politécnico do Portopt_PT
dc.subjectPersonal Care Productspt_PT
dc.subjectPharmaceuticalspt_PT
dc.titleToxicity testing of simvastatin, sertraline, 4-MBC propylparaben and triclocarban using zebrafish and sea urchin embryos bioassayspt_PT
dc.typebook part
dspace.entity.typePublication
oaire.citation.conferencePlacePortopt_PT
oaire.citation.endPage272pt_PT
oaire.citation.issuept_PT
oaire.citation.startPage271pt_PT
oaire.citation.titleICEH14 /3rd International Congress of Environmental Health: Proceedings Bookpt_PT
oaire.citation.volume1pt_PT
person.familyNameMartins
person.givenNameRosario
person.identifier.ciencia-idA919-DB40-EF10
person.identifier.orcid0000-0002-9882-4651
person.identifier.scopus-author-id21834368700
rcaap.rightsopenAccesspt_PT
rcaap.typebookPartpt_PT
relation.isAuthorOfPublication82a7c349-c88e-450f-adc7-3331d69149cf
relation.isAuthorOfPublication.latestForDiscovery82a7c349-c88e-450f-adc7-3331d69149cf

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