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Evaluation of quinoxaline-1,4-dioxide and derivatives biological activity in normal and tumour cell

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Resumo(s)

Quinoxaline derivatives are synthetic heterocyclic compounds with multiples pharmacological applications and biological effects. Previous studies of our group about the biological activity in eukaryotic and prokaryotic microbial models with quinoxaline-1,4-dioxide (QNX) derivatives concluded a selective antimicrobial activity in gram negative strains. To further evaluate these compounds’ potential, we investigated the biologic activity in vitro of this chemical structures in normal and tumour cells lines.

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Quinoxaline-1 4-dioxide and derivatives Normal and tumour cell IC50

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Citação

Silva, L., Coelho, P., Soares, R., Prudêncio, C., & Vieira, M. (2018). Evaluation of quinoxaline-1,4-dioxide and derivatives biological activity in normal and tumour cell. Book of abstracts of the III Encontro de Biotecnologia Medicinal/ I Iberian Congress on Medicinal Biotechnology, 24. https://paginas.ess.ipp.pt/ebtm/2018/3EBtM_BookOfAbstracts.pdf

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