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A throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soils

2016Journal article Restricted access
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dc.contributor.authorPaíga, Paula
dc.contributor.authorDelerue-Matos, Cristina
dc.date.accessioned2017-01-12T10:30:26Z
dc.date.embargo2116
dc.date.issued2016
dc.description.abstractQuick, easy, cheap, effective, rugged, and safe extraction is a modern sample preparation method that involves a number of steps with a low susceptibility to error. The efficiency of a laboratory can be improved not only through labor reduction and consumable savings but also through the use of high-throughput methods and the reduction of wastes. In commercially available kits, different salts and buffers are mixed in anhydrous packages. The composition of these kits are optimized and fixed for particular applications by the suppliers. In this work three model compounds (ibuprofen and two of its main metabolites: hydroxyibuprofen and carboxyibuprofen) were chosen and the amount of each salt (magnesium sulfate, sodium chloride, sodium citrate, and disodium citrate sesquihydrate) in the quick, easy, cheap, effective, rugged, and safe content was optimized for three different soil samples (soils A, B, and C) with different organic carbon contents, using a 24 factorial design. The optimized extraction procedure was applied to 12 soil samples; ranging from river sediments to agricultural soils. Based on the analysis 100 samples, a price reduction of 5.1- (soil B), 5.7- (Soil C), and 6.1-fold (soil A) was achieved without compromising the performance of the method when compared to commercial kits.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1002/jssc.201600412pt_PT
dc.identifier.issn1615-9314
dc.identifier.urihttp://hdl.handle.net/10400.22/9231
dc.language.isoengpt_PT
dc.publisherWiley-VCH Verlagpt_PT
dc.relation.ispartofseriesJournal of Separation Science;Vol. 39, Issue 17
dc.relation.publisherversionhttp://onlinelibrary.wiley.com/doi/10.1002/jssc.201600412/fullpt_PT
dc.subjectIbuprofenpt_PT
dc.subjectMetabolitespt_PT
dc.subjectQuEChERSpt_PT
dc.subjectResponse surface methodologypt_PT
dc.subjectSoilpt_PT
dc.titleA throughput method using the quick easy cheap effective rugged safe method for the quantification of ibuprofen and its main metabolites in soilspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage3444pt_PT
oaire.citation.issue17pt_PT
oaire.citation.startPage3436pt_PT
oaire.citation.titleJournal of Separation Sciencept_PT
oaire.citation.volume39pt_PT
person.familyNamePaíga
person.familyNameDelerue-Matos
person.givenNamePaula
person.givenNameCristina
person.identifier1668889
person.identifier.ciencia-id331A-5D6A-D3C8
person.identifier.ciencia-id9A1A-43FB-5C27
person.identifier.orcid0000-0002-9593-1355
person.identifier.orcid0000-0002-3924-776X
person.identifier.ridQ-4930-2018
person.identifier.ridD-4990-2013
person.identifier.scopus-author-id6506638953
person.identifier.scopus-author-id6603741848
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4a0677dc-0b54-4831-aa9a-4a73f0df911d
relation.isAuthorOfPublication09f6a7bd-2f15-42b0-adc5-04bd22210519
relation.isAuthorOfPublication.latestForDiscovery4a0677dc-0b54-4831-aa9a-4a73f0df911d

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