Publication
Exploring the antiradical potential of species from Lamiaceae family: implications for functional food development in the context of neurodegenerative and neuropsychiatric diseases
| dc.contributor.author | Campinho, Ana | |
| dc.contributor.author | Alves, Joana | |
| dc.contributor.author | Martins, Rosário | |
| dc.contributor.author | Vieira, Mónica | |
| dc.contributor.author | Grosso, Clara | |
| dc.contributor.author | Delerue-Matos, Cristina | |
| dc.date.accessioned | 2024-02-01T12:08:42Z | |
| dc.date.available | 2024-02-01T12:08:42Z | |
| dc.date.issued | 2023-10-30 | |
| dc.description.abstract | Neurodegenerative and neuropsychiatric diseases have become highly significant in Western societies. Unfortunately, these diseases currently lack a cure, and existing treatments merely manage the symptoms. Thus, it is imperative to explore new alternatives for either preventing these disorders or treating them effectively. One promising avenue for prevention lies in the development of neuroprotective and antioxidant functional foods. To this end, a study focused on ten species from the Lamiaceae family, which have attracted attention due to their well-known antioxidant, anti-inflammatory, anti-obesity, and anti-cancer properties, among others. The interest in their pharmacological applications has grown significantly in recent years. In order to uncover the biological potential of these species, the study involved performing decoctions and evaluating both the total phenolic content (TPC) and antiradical activity. The results revealed that TPC values ranged from 59.97 ± 6.18 (Ocimum basilicum L. var minimum) to 374.0 ± 16.9 (Salvia officinalis L.) mg gallic acid equivalents (GAE)/g of dry extract (dw). Additionally, the IC50 values for DPPH• and ABTS•+ scavenging activities varied between 21.55 ± 1.18 (Origanum vulgare L.) and 132.0 ± 15.3 μg/mL (O. basilicum var minimum), and from 14.79 ± 0.50 (O. vulgare) to 44.65 ± 2.34 μg/mL (O. basilicum), respectively. The observed strong antiradical activity holds great promise for the future development of functional foods aimed at combating the oxidative stress implicated in these diseases and promoting overall brain health. By harnessing the potential of these species from Lamiaceae family, we may pave the way for innovative approaches to tackle neurodegenerative and neuropsychiatric conditions. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Campinho, A., Alves, J., Martins, R., Vieira, M., Grosso, C., & Delerue-Matos, C. (2023). Exploring the antiradical potential of species from Lamiaceae family: Implications for functional food development in the context of neurodegenerative and neuropsychiatric diseases. Em A. K. Bhunia (Ed.), The 4th International Electronic Conference on Foods: Biology and Life Sciences forum vol. 26 (1; p. 33). MDPI. https://doi.org/10.3390/Foods2023-15493 | pt_PT |
| dc.identifier.doi | 10.3390/Foods2023-15493 | pt_PT |
| dc.identifier.issn | 2673-9976 | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/24925 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | MDPI | pt_PT |
| dc.relation | This work was supported by projects REQUIMTE/LAQV—UIDB/50006/2020, UIDP/50006/2020, and LA/P/0008/2020 financed by FCT/Ministério da Ciência, Tecnologia e Ensino Superior (MCTES), through national funds. | pt_PT |
| dc.relation.publisherversion | https://www.mdpi.com/2673-9976/26/1/33 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Lamiaceae family | pt_PT |
| dc.subject | Brain disorders | pt_PT |
| dc.subject | Functional foods | pt_PT |
| dc.subject | Oxidative stress | pt_PT |
| dc.title | Exploring the antiradical potential of species from Lamiaceae family: implications for functional food development in the context of neurodegenerative and neuropsychiatric diseases | pt_PT |
| dc.type | conference object | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 5 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| oaire.citation.title | Biology and life sciences forum - 4th International Electronic Conference on Foods | pt_PT |
| oaire.citation.volume | 26 (1) | pt_PT |
| person.familyName | Martins | |
| person.familyName | Vieira | |
| person.givenName | Rosario | |
| person.givenName | Mónica | |
| person.identifier.ciencia-id | A919-DB40-EF10 | |
| person.identifier.orcid | 0000-0002-9882-4651 | |
| person.identifier.orcid | 0000-0002-9614-9031 | |
| person.identifier.rid | D-8977-2016 | |
| person.identifier.scopus-author-id | 21834368700 | |
| person.identifier.scopus-author-id | 24464652500 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | conferenceObject | pt_PT |
| relation.isAuthorOfPublication | 82a7c349-c88e-450f-adc7-3331d69149cf | |
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