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Metabolic syndrome and inflammation: is there a microvascular and an incretin system impairment in the gastrointestinal tract?

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Metabolic syndrome is a multifactorial disorder characterized by increased plasma levels of glucose, cholesterol and triglycerides, but also overweight and obesity promoted by increase of body fat mass, alterations in oxidative stress, chronic low grade inflammation and resistance to insulin leading to risk of cardiovascular diseases. The stomach and the intestine have an essential role in metabolism with functions of digesting food and absorption of nutrients. Also, the intestine produces incretin hormones, such as GLP-1 which regulates glucose metabolism and processes of the gastrointestinal tract.

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Metabolic syndrome Inflammation Incretin system Microvasculature Gastrointestinal tract

Citation

Costa, J., Almeida, J., Coelho, P., Oliveira, S., Prudêncio, C., Soares, R., Gomes-Guerreiro, S., & Fernandes, R. (2016, novembro). Metabolic syndrome and inflammation: Is there a microvascular and an incretin system impairment in the gastrointestinal tract? [Poster]. 8º Simpósio em Metabolismo da Faculdade de Medicina da Universidade do Porto - Revista Portuguesa de Diabetes, Porto.

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