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Helthcare professionals´ knowledge, attitudes and practices in radiopharmaceuticals pharmacovigilance: contributions to the development and validation of a questionnaire

dc.contributor.advisorJesus, Ângelo
dc.contributor.authorArruda, Nathalia Maciel de
dc.date.accessioned2025-02-20T11:13:26Z
dc.date.available2025-02-20T11:13:26Z
dc.date.issued2024-11-29
dc.date.submitted2024-11-29
dc.description.abstractPharmacovigilance monitors the safety of medications, vacines, and biological substances, promoting their rational use and preventing adversa reactions. Spontaneous reporting of ADR sis the primary method of pharmacovigilance, generating alerts to minimize risks. Despite its importance, these events are often underreported. In the case of radiopharmaceuticals, this monitoring is more complex due to the possibility of delayed reactions and underreporting. A scoping review was conducted of questionnaires that assess knowledge, attitudes, and practices of pharmacovigilance among healthcare professionals, and the Delphi method was applied to develop a questionnaire in portuguese for this evaluation. The scoping study resulted in 14 studies that served as the Foundation for the development of a new questionnaire, which aims to assess healthcare professionals’ understanding and practices related to radiopharmaceutical pharmacovigilance. The developed questionnaire contains 42 questions, divided into four sections: Sociodemographic Data, Knowledge about Pharmacovigilance, Attitudes and Practices Regarding Reporting Adversa Reactions to Radiopharmaceuticals, and Motivations and Barriers to Regarding Adversa Reactions to Radiopharmaceuticals. A validated questionnaire developed through a Delphi study emphasized the need for acessible reporting systems and ongoing education for professionals. Establishing na eficiente reporting culture is crucial for ensuring patient safety and optimizing the clinical use of radiopharmaceuticals.por
dc.identifier.tid203863950
dc.identifier.urihttp://hdl.handle.net/10400.22/29610
dc.language.isoeng
dc.rights.uriN/A
dc.subjectPharmacovigilance
dc.subjectHelthcare professoals´
dc.subjectRadiopharmaceutical
dc.subjectSpontaneous reports
dc.subjectNuclear medicine
dc.subjectquestionnaire
dc.subjectAdverse drug reactions
dc.subjectPortugal
dc.subjectAdverse reation notification
dc.titleHelthcare professionals´ knowledge, attitudes and practices in radiopharmaceuticals pharmacovigilance: contributions to the development and validation of a questionnairepor
dc.typemaster thesis
dspace.entity.typePublication

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