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Sources of bias when assessing seasonal Influenza vaccine performance: a narrative review

dc.contributor.authorMartins, André Miguel
dc.contributor.authorJuan, Luis Félix Valero
dc.contributor.authorSantos, Marlene
dc.contributor.authorMartins, João Paulo
dc.date.accessioned2025-03-27T12:45:41Z
dc.date.available2025-03-27T12:45:41Z
dc.date.issued2025-01-11
dc.description.abstractThe best way to prevent influenza infection is through vaccination. Evaluating vaccine performance is essentially done through two types of study: clinical trials and the test negative design, an observational study derived from the case control. While in clinical trials the sources of bias are perfectly identified and there are specific tools for assessing them, in test negative design we find very varied sources of bias and a lot of scattered information without there being a validated tool for assessing the risk of bias. The aim of this narrative review is to identify the most important sources of bias in both types of study and to contribute to the development of a risk assessment tool for test negative design studies, given their major importance in evaluating the performance of the seasonal influenza vaccine.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMartins, A. M., Juan, L. F. V., Santos, M., & Martins, J. P. (2025). Sources of bias when assessing seasonal Influenza vaccine performance: A narrative review. Em L. Henriques-Rodrigues, R. Menezes, L. M. Machado, S. Faria, & M. de Carvalho (Eds.), New Frontiers in Statistics and Data Science (SPE 2021) (Vol. 469, pp. 211–228). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-68949-9_16pt_PT
dc.identifier.doi10.1007/978-3-031-68949-9_16pt_PT
dc.identifier.isbn978-3-031-68948-2; EISBN978-3-031-68949-9
dc.identifier.urihttp://hdl.handle.net/10400.22/29903
dc.language.isoengpt_PT
dc.peerreviewedyes
dc.publisherSpringer Naturept_PT
dc.relationUIDB/00006/2020
dc.relation.hasversionhttps://link.springer.com/chapter/10.1007/978-3-031-68949-9_16
dc.relation.publisherversionhttps://link.springer.com/chapter/10.1007/978-3-031-68949-9_16pt_PT
dc.rights.uriN/A
dc.subjectVaccinept_PT
dc.subjectEffcacypt_PT
dc.subjectEffectivenesspt_PT
dc.subjectTest negative designpt_PT
dc.subjectBias assessmentpt_PT
dc.subjectEstimationpt_PT
dc.titleSources of bias when assessing seasonal Influenza vaccine performance: a narrative reviewpt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferenceDate2021
oaire.citation.endPage228pt_PT
oaire.citation.startPage211pt_PT
oaire.citation.titleNew Frontiers in Statistics and Data Science (SPE 2021)pt_PT
oaire.citation.volume469pt_PT
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameSantos
person.familyNameOliveira Martins
person.givenNameMarlene
person.givenNameJoão Paulo
person.identifier1508370
person.identifier955929
person.identifier.ciencia-id8311-B967-31C4
person.identifier.ciencia-id6913-C065-48FF
person.identifier.orcid0000-0001-5020-5942
person.identifier.orcid0000-0002-0474-1397
person.identifier.scopus-author-id57110502000
person.identifier.scopus-author-id55838096100
rcaap.rightsclosedAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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relation.isAuthorOfPublication9d1f7388-bb3e-4f1d-bf41-08a589b1d6a8
relation.isAuthorOfPublication.latestForDiscovery9d1f7388-bb3e-4f1d-bf41-08a589b1d6a8

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