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Food and lifestyle determinants of maternal exposure to semi-metal and heavy metal pollutants

dc.contributor.authorGuimarães, Juliana
dc.contributor.authorBracchi, Isabella
dc.contributor.authorPinheiro, Cátia
dc.contributor.authorVieira, Maria Inês
dc.contributor.authorBarbosa, Margarida Oliveira
dc.contributor.authorAlmeida, Agostinho
dc.contributor.authorAzevedo, Rui
dc.contributor.authorPinto, Edgar
dc.contributor.authorPestana, Diogo
dc.contributor.authorCalhau, Conceição
dc.contributor.authorPrucha, Maria do Carmo
dc.contributor.authorMartins, Cristina
dc.contributor.authorDias, Cláudia C.
dc.contributor.authorAzevedo, Luís Filipe R.
dc.contributor.authorRamalho, Carla
dc.contributor.authorFernandes, Virgínia Cruz
dc.contributor.authorKeating, Elisa
dc.contributor.authorFernandes, Virgínia
dc.contributor.authorPinto, Edgar
dc.date.accessioned2026-07-10T14:34:44Z
dc.date.available2026-07-10T14:34:44Z
dc.date.issued2025-06
dc.description.abstractExposure to toxics elements such as Lead (Pb), Cadmium (Cd), Lithium (Li) and Arsenic (As) pose health risks particularly for vulnerable groups like pregnant women and children. Knowledge about toxic metal exposure in these groups is scarce in Portugal. This study aims to identify food and lifestyle determinants of maternal exposure to toxic elements. Pregnant women from the IoMum cohort, undergoing firsttrimester fetal ultrasound between April 2018 and December 2021 at CHUSJoão (Porto) and Hospital CUF Descobertas (Lisbon), were invited to participate. At this stage, dietary and lifestyle information was collected through a structured questionnaire. A random urine sample was collected for Pb, Cd, Li and total (inorganic + organic) As quantification by ICP-MS and the values were adjusted for urinary creatinine concentration. A total of 305 mother: child pairs were included. RESULTS: The majority of the sample had detectable urinary levels of toxic elements (n (%): 269 (88), 157 (52), 305 (100) and 293 (96) for Pb, Cd, Li and total As, respectively). Pb urinary concentration was inversely associated with education level (p=0.008) while Cd and As levels were positively associated with education level (p=<0.001 and 0.002, respectively). Smoking was associated with higher Pb levels (p<0.001). Fish intake frequency was positively associated with Cd and As levels (p=0.005 and p<0.001, respectively) with women with fish intake higher than 4 times a week presenting median (P25;P75) in μg/g total As 33.8 (20.9 ; 67.7) concentration above the reference range typically (≥ 24.0 μg/g), seen in a group of healthy individuals. On the other hand, milk intake frequency was inversely associated Pb levels (p=0.025). Our results suggest that fish consumption may be a significant source of Cd and As exposure and that a higher milk intake may have a protective effect against Pb exposure.eng
dc.identifier.citationGuimarães, J., Bracchi, I., Pinto, E., & Fernandes, V. C. (2025). Food and lifestyle determinants of maternal exposure to semi-metal and heavy metal pollutants. Food and lifestyle determinants of maternal exposure to semi-metal and heavy metal pollutants, 41, 98–99. https://actaportuguesadenutricao.pt/wp-content/uploads/2025/09/ACTA-41_LOW-2.pdf
dc.identifier.issn2183-5985
dc.identifier.urihttp://hdl.handle.net/10400.22/32576
dc.language.isoeng
dc.peerreviewedyes
dc.publisherAssociação Portuguesa de Nutrição
dc.relation.hasversionhttps://actaportuguesadenutricao.pt/wp-content/uploads/2025/09/ACTA-41_LOW-2.pdf
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectFood
dc.subjectMetal
dc.titleFood and lifestyle determinants of maternal exposure to semi-metal and heavy metal pollutantseng
dc.typeconference poster
dspace.entity.typePublication
oaire.citation.conferenceDate2025-05
oaire.citation.conferencePlaceBraga
oaire.citation.endPage99
oaire.citation.startPage98
oaire.citation.titleXXIV Congresso de Nutrição e Alimentação da Associação Portuguesa de Nutrição (APN) 2025 - Acta Portuguesa de Nutrição
oaire.citation.volume41
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameFernandes
person.familyNamePinto
person.givenNameVirgínia
person.givenNameEdgar
person.identifier.ciencia-id5A16-3713-E0CE
person.identifier.ciencia-id271F-B7DF-8FAB
person.identifier.orcid0000-0003-3979-7523
person.identifier.orcid0000-0002-8021-4783
person.identifier.ridG-4985-2010
person.identifier.scopus-author-id37045954500
relation.isAuthorOfPublicatione30d74c3-1a3a-4e3e-ada0-5e79362cdd6e
relation.isAuthorOfPublicationeaf9fc86-1a1c-437f-adee-d28040aa7f2f
relation.isAuthorOfPublication.latestForDiscoverye30d74c3-1a3a-4e3e-ada0-5e79362cdd6e

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