Bioactivity screening of marine cyanobacteria for the isolation of novel compounds for hepatic steatosis

Moreira, Gabriela A.; Rosa, Filipa; Vasconcelos, Vítor; Urbatzka, Ralph

http://hdl.handle.net/10400.22/25663

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Abstract(s)

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease and effective therapeutics has been widely study. Cyanobacteria, previously known as blue-green algae, are known to produce many secondary metabolites including toxins, with applications to the pharmaceutical industry. The aim of this study is to investigate the effect of extract from cyanobacteria to reduce lipid accumulation in a model of hepatic steatosis using HepG2 cells in vitro.

Keywords

Steatosis Cyanobacteria HepG2 cells Bioactive compounds

URI

http://hdl.handle.net/10400.22/25663

Citation

Moreira, G., Rosa, F., Vasconcelos, V., & Urbatzka, R. (2018). Bioactivity screening of marine cyanobacteria for the isolation of novel compounds for hepatic steatosis. Book of abstracts of the III Encontro de Biotecnologia Medicinal/ I Iberian Congress on Medicinal Biotechnology, 32. https://paginas.ess.ipp.pt/ebtm/2018/3EBtM_BookOfAbstracts.pdf