Browsing by Author "Soares, Ana Paula"
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- Auditory N1, N2, and MMN to pure-tone and consonant–vowel stimuli in developmental dyslexia and benign rolandic epilepsy: A progressive insight into the underlying disruptive neurophysiologyPublication . Tomé, David; Pereira, Ilídio; Vieira, Maria Celeste; Soares, Ana Paula; Barbosa, FernandoBenign rolandic epilepsy or benign epilepsy in childhood with centrotemporal spikes (BECTS) and developmental dyslexia (DD) are two of the most studied disorders in childhood. Despite decades of research, the neurophysiological mechanisms underpinning these disorders are largely unknown. Here, we use auditory event-related potentials (AERPs) to shed light on these issues, since several authors have reported the existence of language and learning impairments. AERPs reflect the activation of different neuronal populations and are suggested to contribute to the evaluation of auditory discrimination (N1), attention allocation and phonological categorization (N2), and echoic memory (mismatch negativity (MMN]). This study aims to investigate and document AERP changes in a group of children with BECTS and another group with DD. AERPs were recorded to pure-tones and consonant–vowel (CV) stimuli in an auditory oddball paradigm in eight children with BECTS, seven with DD, and 11 gender- and age-matched controls. The results revealed perceptual deficits for pure-tone and CV stimuli (pre-attentional and auditory discrimination) in DD, related to N1 reduced amplitude (p< 0.05; Fz: 2.57 μV, Cz: 2.75 μV). The BECTS group revealed no significant results for N1; however, there was an increase in N2b latency. The findings in the DD group support the anchor-deficit hypothesis as an explanation for neurolinguistic deficits. The increased N2b latency in the BECTS group could be related to a potential lack of inhibitory mechanisms of pyramidal neurons, as justified by the process of epileptogenesis.
- Neurodevelopmental correlates of implicit-explicit learning mechanisms in children with specific language impairmentPublication . Soares, Ana Paula; Gutiérrez-Domínguez, Francisco-Javier; Vasconcelos, Margarida; Oliveira, Helena M.; Tomé, David; Lousada, Marisa; Jiménez, LuisThis project has the grant POCI-01-0145-FEDER-028212, started in June of 2019 ending in May of 2022, with researchers from ESS | P. PORTO, University of Minho and University of Aveiro. Aims to analyze the neurocognitive correlates of implicit-explicit learning mechanisms in preschool specific-learning impairment (SLI) children and to track their developmental trajectories until they enter primary school. Studies aiming to explore the nature and dynamics of procedural memory-declarative memory functioning in SLI using brain techniques and following the same children on time are inexistent. This project aims to address these issues by combining an artificial grammar paradigm with ERPs in a longitudinal design, which will contribute not only to clarify the role of procedural memory deficits-declarative memory compensation on SLI, but also to the development of effective intervention programs for children who are at risk of dyslexia
- Not all words are equally acquired: Transitional probabilities and instructions affect the electrophysiological correlates of statistical learningPublication . Soares, Ana Paula; Gutiérrez-Domínguez, Francisco-Javier; Vasconcelos, Margarida; Oliveira, Helena M.; Tomé, David; Jiménez, Luís