Browsing by Author "Martins, F."
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- Buildings Sustainability — The Non-Intrusive Load-Identification System ContributionPublication . Felgueiras, Carlos; Cruz, N.; Martins, F.; Martins, R.Buildings are responsible for an important share of the global energy consumed with the associated consequences at economic and environmental level. To overcome this actual concern several objectives were put in perspective, being one of them the energetic performance of systems and appliances. Efficiency depends on working on optimal conditions and user behavior. Monitoring of the energy consumption of each electric load is important but the use of decentralized energy is not feasible at present due to the huge number of loads connected to the electric grid. An alternative consists on the use of a centralized measurement device able to identify loads. This work presents a measurement infrastructure that have, among others, the possibility to make the identification of electrical loads data will be used to improve the energetic performance of households and buildings and increase the sustainability of the energy system.
- Embedded Electricity Quality AnalyzerPublication . Freitas, S.; Martins, R.; Martins, F.; Felgueiras, CarlosElectric installations are traditionally designed for supplying an electric service. The only one associated instrument is the energy meter that is introduced only for measure the total amount of energy that will be charged to the user. However, the exploration of parameters associated with electricity can provide several advantages such the household performance devices, legal issues and later one a more sustainable way to use the electricity energy. This work presents the principle of a low cost energy analyzer that will be part of an electric home installation. Electric parameters are measured and then transmitted via Wi-Fi to a domestic server where all data are stored. This data exploitation can be later one used for several purposes, since electric efficiency to electric charges prediction.
- Influence of KRAS activation in the colorectal cancer immunosurveillance escapePublication . Machado, Ana Luísa; Mendonça, S.; Carvalho, P. Dias; Martins, F.; Oliveira, M. J.; Velho, S.The immune system as a host defense system watches the cell growth and division, eliminating cells with antigens different from those present in healthy cells. However, some transformed cells have the capacity, through various mechanisms, to escape the immune system. Genomic instability and some mutations are pointed as possible mechanisms supporting the immunosurveillance escape, as is the case of KRAS mutation. This oncogenic mutation is present in about 30% of cases of colorectal cancer and confers to the tumor a greater potential for malignancy. It is known that KRAS mutant cancer cells regulate the recruitment, activation, and differentiation of immune cells, promoting tumor evolution by ensuring leakage to the immune system and increasing the proliferative potential. Few evidence highlights an association between a KRAS mutation and myeloid cells, mainly macrophages and neutrophils infiltration. However, the mechanism which determines this interaction remains unclear. Due to the growing knowledge of different immunosuppressive molecules, it became interesting to investigate if there is an alteration in these molecules related to the KRAS activation.
- RES Efficiency Indicators for Portugal, Slovakia and Czech RepublicPublication . Smitková, M.; Felgueiras, Carlos; Martins, F.