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Phagetherapies for infections caused by P. aeruginosa
Publication . Ferraz, Ricardo; Reis, Ana; Prudêncio, Cristina; Baylina, Pilar; Fernandes, Rúben; Ferraz, Ricardo; Prudêncio, Cristina; BAYLINA MACHADO, PILAR; Fernandes, Rúben
The hospital infections can be prevented by controlling some factors related with staff, material, and environment. At this moment the existing legislation regulates procedures that prevent the propagation of the infection and/or of the agents that causes it. The Pseudomonas aeruginosa is a gram-negative opportunistic responsible for most of the hospital infections. Because it is opportunistic it is more frequent in immunocompromised patients submitted to transplants and surgical interventions. In short, this thesis has contributed for the understanding of the biology of P. aeruginosa , antibacterial treatment and its resistance to this treatment by using efflux bombs, and so as establishing associations with others factors, such as biochemical. This study has the objective to understand the resistance factors used by the P. aeruginosa in order to develop alternative therapies for this agent. Initially, 72 hospitalar isolated were characterized and 91.67% have revealed more than 3 classes of Antimicrobians.
2013-10Conference paper not in proceedings Open access Show more