Psychotropic drugs and liver disease: a critical review of pharmacokinetics and liver toxicity

Telles-Correia, Diogo; Barbosa, António; Cortez-Pinto, Helena; Campos, Carlos; Rocha, Nuno; Machado, Sérgio

http://hdl.handle.net/10400.22/18006

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Authors

Telles-Correia, Diogo

Abstract(s)

The liver is the organ by which the majority of substances are metabolized, including psychotropic drugs. There are several pharmacokinetic changes in end-stage liver disease that can interfere with the metabolization of psychotropic drugs.

Keywords

Liver Toxicity Psychotropic drugs Pharmacokinetics Hepatic disease

URI

http://hdl.handle.net/10400.22/18006

Citation

Telles-Correia D, Barbosa A, Cortez-Pinto H, Campos C, Rocha NBF, Machado S. Psychotropic drugs and liver disease: A critical review of pharmacokinetics and liver toxicity. World J Gastrointest Pharmacol Ther 2017; 8(1): 26-38 [PMID: 28217372 DOI: 10.4292/wjgpt.v8.i1.26]