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Gold nanoparticles covalently assembled onto vesicle structures as possible biosensing platform

2016Journal article Open access
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dc.contributor.authorBarroso, M. Fátima
dc.contributor.authorLuna, M. Alejandra
dc.contributor.authorTabares, Juan S. Flores
dc.contributor.authorDelerue-Matos, Cristina
dc.contributor.authorCorrea, N. Mariano 
dc.contributor.authorMoyano, Fernando
dc.contributor.authorMolina, Patricia G.
dc.date.accessioned2017-01-13T10:50:15Z
dc.date.available2017-01-13T10:50:15Z
dc.date.issued2016
dc.description.abstractIn this contribution a strategy is shown to covalently immobilize gold nanoparticles (AuNPs) onto vesicle bilayers with the aim of using this nanomaterial as platform for the future design of immunosensors. A novel methodology for the self-assembly of AuNPs onto large unilamellar vesicle structures is described. The vesicles were formed with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1-undecanethiol (SH). After, the AuNPs photochemically synthesized in pure glycerol were mixed and anchored onto SH–DOPC vesicles. The data provided by voltammetry, spectrometry and microscopy techniques indicated that the AuNPs were successfully covalently anchored onto the vesicle bilayer and decorated vesicles exhibit a spherical shape with a size of 190 ± 10 nm. The developed procedure is easy, rapid and reproducible to start designing a possible immunosensor by using envi-ronmentally friendly procedures.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3762/bjnano.7.58pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/9254
dc.language.isoengpt_PT
dc.publisherBeilstein-Institutpt_PT
dc.relation.ispartofseriesBeilstein Journal of Nanotechnology;Nº 7
dc.relation.publisherversionhttp://www.beilstein-journals.org/bjnano/single/articleFullText.htm?publicId=2190-4286-7-58pt_PT
dc.subjectCovalently decorated vesiclespt_PT
dc.subjectGold nanoparticlespt_PT
dc.subjectImmunosensors designpt_PT
dc.subjectSynthesispt_PT
dc.titleGold nanoparticles covalently assembled onto vesicle structures as possible biosensing platformpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage663pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage655pt_PT
oaire.citation.titleBeilstein Journal of Nanotechnologypt_PT
person.familyNamede Sá Barroso
person.familyNameDelerue-Matos
person.givenNameMaria de Fátima
person.givenNameCristina
person.identifier.ciencia-idAF16-22E5-5EBD
person.identifier.ciencia-id9A1A-43FB-5C27
person.identifier.orcid0000-0001-9011-5992
person.identifier.orcid0000-0002-3924-776X
person.identifier.ridD-4990-2013
person.identifier.scopus-author-id25631648000
person.identifier.scopus-author-id6603741848
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication3d701c85-4580-4614-be6d-5a1abc8cf729
relation.isAuthorOfPublication09f6a7bd-2f15-42b0-adc5-04bd22210519
relation.isAuthorOfPublication.latestForDiscovery3d701c85-4580-4614-be6d-5a1abc8cf729

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