Publication
Electrochemical determination of citalopram by adsorptive stripping voltammetry–determination in pharmaceutical products
| dc.contributor.author | Nouws, Henri P. A. | |
| dc.contributor.author | Delerue-Matos, Cristina | |
| dc.contributor.author | Barros, Aquiles A. | |
| dc.date.accessioned | 2013-11-26T16:54:19Z | |
| dc.date.available | 2013-11-26T16:54:19Z | |
| dc.date.issued | 2006 | |
| dc.description.abstract | The electrochemical behavior of citalopram was studied by square-wave and square-wave adsorptive-stripping voltammetry (SWAdSV). Citalopram can be reduced and accumulated at a mercury drop electrode, with a maximum peak current intensity being obtained at a potential of approximately -1.25V vs. AgCl/Ag, in an aqueous electrolyte solution of pH 12. A SWAdSV method has been developed for the determination of citalopram in pharmaceutical preparations. The method shows a linear range between 1.0x10-7 and 2.0x10-6 mol L-1 with a limit of detection of 5x10-8 mol L-1 for an accumulation time of 30 s. The precision of the method was evaluated by assessing the repeatability and intermediate precision, achieving good relative standard deviations in all cases (≤2.3%). The proposed method was applied to the determination of citalopram in five pharmaceutical products and the results obtained are in good agreement with the labeled values. | por |
| dc.identifier.doi | 10.1080/00032710600721712 | pt_PT |
| dc.identifier.issn | 0003-2719 | |
| dc.identifier.issn | 1532-236X | |
| dc.identifier.uri | http://hdl.handle.net/10400.22/2969 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Taylor & Francis | por |
| dc.relation.ispartofseries | Analytical Letters; Vol. 39, Issue 9 | |
| dc.relation.publisherversion | http://www.tandfonline.com/doi/abs/10.1080/00032710600721712#.UpS-J0r6Q25 | por |
| dc.subject | Citalopram | por |
| dc.subject | SSRI | por |
| dc.subject | Hanging mercury drop electrode | por |
| dc.subject | Adsorptive-stripping voltammetry | por |
| dc.subject | Pharmaceutical analysis | por |
| dc.title | Electrochemical determination of citalopram by adsorptive stripping voltammetry–determination in pharmaceutical products | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 1915 | por |
| oaire.citation.startPage | 1907 | por |
| oaire.citation.title | Analytical Letters | por |
| oaire.citation.volume | 39 | por |
| person.familyName | Delerue-Matos | |
| person.givenName | Cristina | |
| person.identifier.ciencia-id | 9A1A-43FB-5C27 | |
| person.identifier.orcid | 0000-0002-3924-776X | |
| person.identifier.rid | D-4990-2013 | |
| person.identifier.scopus-author-id | 6603741848 | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
| relation.isAuthorOfPublication | 09f6a7bd-2f15-42b0-adc5-04bd22210519 | |
| relation.isAuthorOfPublication.latestForDiscovery | 09f6a7bd-2f15-42b0-adc5-04bd22210519 |