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Abstract(s)
A Cochlospermum angolensis (Borututu) é uma planta com propriedades medicinais
utilizada para o tratamento de patologia hepática e na profilaxia contra a malária. No
entanto, são necessários mais estudos para comprovar a sua composição química e a sua
atividade biológica.
Como a utilização desta planta é recorrente no seio da população angolana, o objetivo
deste estudo foi descrever o estado de arte para a sua utilização, através do conhecimento
popular e revisão bibliográfica existente; e avaliar a sua bioatividade, com a proporção
de extratos aquosos e orgânicos e caraterização da bioatividade dos mesmos em
organismos unicelulares, nomeadamente, bactérias e leveduras.
Os extratos orgânicos e aquosos foram obtidos pela técnica de extração clássica,
utilizando como solventes: água destilada, hexano, metanol, mistura metanol/água
(50:50) e dimetilsulfóxido.
Com o desenvolvimento deste trabalho pretendeu-se contribuir para a elucidação da
atividade biológica do Borututu, uma vez que é uma planta bastante utilizada em Angola,
para fins medicinais. Os resultados obtidos indicam que a C. angolensis (Borututu)
apresenta, na sua constituição, compostos químicos que lhe conferem propriedades de
inibição do crescimento de bactérias e leveduras. Com estes resultados, pode-se inferir
que o Borututu poderá apresentar propriedades de interesse para as indústrias
farmacêutica e alimentar.
Introduction: Cochlospermum angolensis (Burututu) is a plant with medical properties used for the treatment of hepatic pathology and in prophylaxis against malaria. However, further studies are needed to prove its chemical composition and biological activity. Objectives: As the use of this plant is recurrent within the Angolan population, the main objectives of this study were to describe the state of art for its use, through popular knowledge and existing bibliographic literature; and to evaluate its bioactivity, with the proportion of aqueous and organic extracts and charcaterization of the bioactivity of the extracts obtained in unicelular organisns, namely, bactéria and yeasts. Methods: Organic and aqueous extacts were obtained by the classical extraction technique, using as solvente: distilld water, hexane, metanol, metanol/water (50:50) and dimethylsufoxide. Conclusion: With the development of this work, it was intended to contribute to the elucidation of the biological activity of Borututu, since i tis a plant widely used in Angola for medicinal purposes. The results obtained indicate that C. angolensis (Borututu) has chemical compounds which have inhibitory properties against bactéria and yeasts. With these results, it can be inferred that Borututu may presente properties of interest to the pharmaceutical and food industries.
Introduction: Cochlospermum angolensis (Burututu) is a plant with medical properties used for the treatment of hepatic pathology and in prophylaxis against malaria. However, further studies are needed to prove its chemical composition and biological activity. Objectives: As the use of this plant is recurrent within the Angolan population, the main objectives of this study were to describe the state of art for its use, through popular knowledge and existing bibliographic literature; and to evaluate its bioactivity, with the proportion of aqueous and organic extracts and charcaterization of the bioactivity of the extracts obtained in unicelular organisns, namely, bactéria and yeasts. Methods: Organic and aqueous extacts were obtained by the classical extraction technique, using as solvente: distilld water, hexane, metanol, metanol/water (50:50) and dimethylsufoxide. Conclusion: With the development of this work, it was intended to contribute to the elucidation of the biological activity of Borututu, since i tis a plant widely used in Angola for medicinal purposes. The results obtained indicate that C. angolensis (Borututu) has chemical compounds which have inhibitory properties against bactéria and yeasts. With these results, it can be inferred that Borututu may presente properties of interest to the pharmaceutical and food industries.
Description
Keywords
Cochlospermum angolensis Plantas medicinais Borututu Bioactividade de compostos