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Determination of pharmaceuticals in groundwater collected in five cemeteries' areas (Portugal)

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There are growing public attention and concern about the possibility of ecosystemand human health effects from pharmaceuticals in environment. Several types of environmental samples were target of studies by the scientific community, namely drinkingwater, groundwater, surfacewater (river, ocean), treated water (influent and effluent), soils, and sediments near to Wastewater Treatment Plants or near to others potential sources of contaminations. Normally, studies in the cemeteries areas are for historical and architectural research and questions of the potential risk for adverse impact of cemeteries in environment have never received enough attention. However, this risk may exist when cemeteries are placed in areas that are vulnerable to contamination. The objective of the present work was the determination of pharmaceuticals (nonsteroidal anti-inflammatory/ analgesics, antibiotics and psychiatric drugs) in groundwater samples collected inside of the cemeteries areas. Acetaminophen, salicylic acid, ibuprofen, ketoprofen, nimesulide, carbamazepine, fluoxetine, and sertraline were the pharmaceuticals achieved in the analysed samples. None of the studied antibiotics were detected. The highest concentration was obtained for salicylic acid (in the range of 33.7 to 71.0 ng/L) and carbamazepine (between 20.0 and 22.3 ng/L), respectively. By the cluster analysis similarity between carbamazepine and fluoxetine was achieved.

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Cemeteries Groundwater Pharmaceuticals Solid phase extraction UHPLC-ESI-MS/MS

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Editora

Elsevier

Licença CC

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