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Adipocyte-released factors enhance melanocyte’s proliferation and motility

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Obesity, favored by the modern lifestyle, acquired epidemic proportions nowadays. Obesity has been associated with various major causes of death and morbidity including malignant neoplasms. Cutaneous melanoma incidence rates have also been increasing uring the last four decades in several countries. Obesity involvement in melanoma etiology has been recognized, but the implicated mechanisms remain unclear. We propose to address the above relationship and investigate the mechanism interplaying between obesity and an increased risk of melanoma onset.

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Keywords

Obesity Melanoma Adipocytes Cancer proliferation Cancer motility

Citation

Fernandes, R., Coelho, P., Almeida, J., Prudêncio, C., & Soares, R. (2013). Adipocyte-Released Factors Enhance Melanocyte’s Proliferation and Motility. 17.º Congresso Português de Obesidade - Da Patogénese à Prevenção da Obesidade, Porto.

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Sociedade Portuguesa de Cirurgia

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