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Cyanobacteria for skin care and cosmeceutical formulations

dc.contributor.authorMelo, Luísa
dc.contributor.authorMorone, Janaína
dc.contributor.authorSilva, Margarida
dc.contributor.authorFerraz, Ricardo
dc.contributor.authorMartins, Rosário
dc.date.accessioned2024-06-07T08:32:11Z
dc.date.available2024-06-07T08:32:11Z
dc.date.issued2022-10-21
dc.description.abstractSkin acts as a barrier from external stimulus such as pollutants and ultraviolet radiation. Disturbs in the skin are involved in skin aging, which mostly results on a thinner epidermis, dryness, wrinkles, and loss of elasticity. Synthetic ingredients in cosmetics are known to be more toxic and to cause negative impact on the environment. In a society increasingly worried with human and environment health, natural skin care products gain special attention and boosted the search for natural sources. Due to the production of bioactive compounds, cyanobacteria emerged as an excellent source for cosmetic ingredients. Cyanobacteria strains of CIIMAR culture collection (LEGE-CC) have already proven to be interesting for cosmetic purposes [1,2]. In this project we aimed to evaluate the potential of four LEGE-CC cyanobacteria strains for skin care purposes. The cytotoxicity of acetonic and aqueous extracts was evaluated in keratinocytes (HaCAT), fibroblasts (3T3L1) and endothelial cells (hCMEC/D3) along with the total phenolic content and antioxidant properties. Cytotoxic assays revealed toxicity of acetonic extracts to keratinocytes in the higher concentrations tested. Aqueous extracts revealed low or non-cytotoxicity. Mainly in low concentrations of extracts, cellular proliferation was registered. Aqueous extracts from strain JM/RS021A and acetone extracts from strain JM/RS035B revealed higher values for total phenolic compounds. The acetone extracts of strain JM/RS021A showed the greatest scavenging activity values on the DPPH assay.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMelo, L., Morone, J., Silva, M., Ferraz, R., & Martins, R. (2022). Cyanobacteria for skin care and cosmeceutical formulations. Book of Abstracts of 5th Meeting of Medicinal Biotechnology (5MBtM) and 2nd Iberian Congress on Medicinal Biotechnology, 20. https://paginas.ess.ipp.pt/ebtm/2022/5EBTM_BookOfAbstracts.pdfpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.22/25630
dc.language.isoengpt_PT
dc.publisherEscola Superior de Saúde P.Portopt_PT
dc.relation.publisherversionhttps://paginas.ess.ipp.pt/ebtm/2022/5EBTM_BookOfAbstracts.pdfpt_PT
dc.subjectCyanobacteriapt_PT
dc.subjectCosmeticspt_PT
dc.subjectSkinpt_PT
dc.subjectPhenols antioxidantpt_PT
dc.titleCyanobacteria for skin care and cosmeceutical formulationspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePortopt_PT
oaire.citation.startPage20pt_PT
oaire.citation.titleBook of Abstracts of 5th Meeting of Medicinal Biotechnology (5MBtM) and 2nd Iberian Congress on Medicinal Biotechnologypt_PT
person.familyNameFerraz
person.familyNameMartins
person.givenNameRicardo
person.givenNameRosario
person.identifier.ciencia-id001E-71CE-F92D
person.identifier.ciencia-idA919-DB40-EF10
person.identifier.orcid0000-0002-1761-117X
person.identifier.orcid0000-0002-9882-4651
person.identifier.ridG-5639-2011
person.identifier.scopus-author-id24464208500
person.identifier.scopus-author-id21834368700
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isAuthorOfPublicationa5a8faa7-12a5-4b1c-bced-44c895677397
relation.isAuthorOfPublication82a7c349-c88e-450f-adc7-3331d69149cf
relation.isAuthorOfPublication.latestForDiscovery82a7c349-c88e-450f-adc7-3331d69149cf

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