Mitochondrial function and acetyl-L-carnitine neuroprotection

Cunha, Lídia; Bravo, Joana; Gonçalves, Raquel; Metello, Luís F.; Rodrigues, Adriano; Summavielle, Teresa

http://hdl.handle.net/10400.22/5541

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Abstract(s)

Mitochondrial dysfunction is involved in a number of chronic neurodegenerative disorders. Acetyl-L-carnitine (ALC) has been proposed to confer effective neuroprotection by increasing mitochondria viability, but little is known regarding the molecular mechanisms involved in its action