The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines

Soares, S.; Guerreiro, S.G.; Sales, M.G.F.; Correa-Duarte, M.; Fernandes, Rúben

http://hdl.handle.net/10400.22/25128

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Abstract(s)

Gold nanoparticles (AuNP) can be applied in medicine to treat many diseases, such as cancer. Over the years, they have attracted a lot of interest for therapies. In this study, we synthetized three different shapes of gold nanoparticles – spherical, stars and rods and analyzed their cytotoxicity in prostate cancer cell lines (PC3, DU145 and LNCaP). Cells were treated with different concentrations of gold nanoparticles, from 0 to 1.0 mM during 24h. The results showed that gold nanoparticles were nontoxic to concentration until 1.0 mM.

Keywords

Gold nanoparticles Cytotoxicity In vitro assay Prostate cancer

URI

http://hdl.handle.net/10400.22/25128

Citation

Soares, S., Guerreiro, S. G., Sales, M. G. F., Correa-Duarte, M., & Fernandes, R. (2021). The effect of shape of gold nanoparticles in cytotoxicity of prostate cancer cell lines. Em J. Belinha, J. C. R. Campos, E. Fonseca, M. H. F. de Silva, M. F. G. Costa, S. Oliveira, & M. A. Marques (Eds.), LIVRO de RESUMOS do 9o CONGRESSO NACIONAL DE BIOMECÂNICA (pp. 232–233). INEGI - Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia Industrial.