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Computacional pathology: What’s new

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Resumo(s)

The term computacional pathology (CPath) has become a buzz-word among the digital pathology community. Adances in scanning systems, imaging technologies and storage devices are generating an ever-increasing volume of whole-slide images (WSI) acquired in clinical settings, which can be computacionally analyzed using artificial intelligence (AI), such as deep learning technologies, in a new área of development called CPath. The purpose of the review is to disseminate the latest news and futures perspectives by CPath. Deep learning in the context of CPath has methodological contributions that can be distinguished into approaches based on the final purpose of the analysis: predicting clinical endpoints such as cancer subtype, patient survival or genetic mutations from WSI and AI-based assistive tools, such as segmentation methods for WSI or virtual staining. The emergence of multipex imaging, spatially resolver genomic assays and 3D pathology, among other methodologies, will accelerate this trend, providing new opportunities for multimodal integration and discovering new biomarkers. Additionally, these developments will help automating labor-intensive manual work and reducing inter-observer variability diagnosis between pathologists, contributing to a better patient care. CPath will underpin the development of the next generation of cancer therapies and diagnostics, changing the clinical research and ultimately leading towards new cures or improved patient outcomes.

Descrição

Palavras-chave

Digital pathology Computacional pathology Artificial intelligence

Contexto Educativo

Citação

Coelho, D., Assunção, T., Borrecho, G., Geraldes, M., Vinagre, T., Ferreira, I., Ferreira, A., Fernandes, A. I., França, A., Vale, J., Curado, M., Mendes, F., & Martins, D. (2024). Computacional pathology: What’s new. Trends in Biomedical Laboratory Sciences - Abstract Book II Congresso BioMedLab, Vol 2 nº1 Supplement, 78. https://biomedlab.pt/wp-content/uploads/2024/03/Abstract-Book_Revista-Vol-2_020324.pdf

Projetos de investigação

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Fascículo

Editora

Associação Portuguesa de Ciências Biomédicas Laboratoriais

Licença CC

Sem licença CC