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Chromatographic methods developed for the quantification of quercetin extracted from natural sources: systematic review of published studies from 2018 to 2022

2023-11-22Journal article Open access
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dc.contributor.authorCarvalho, Daniel
dc.contributor.authorPinho, Cláudia
dc.contributor.authorOliveira, Rita
dc.contributor.authorMoreira, Fernando
dc.contributor.authorOliveira, Ana
dc.date.accessioned2024-02-01T10:17:48Z
dc.date.available2024-02-01T10:17:48Z
dc.date.issued2023-11-22
dc.description.abstractQuercetin (QUE) is the most widely used flavonoid for therapeutic purposes. To improve the available knowledge about the properties of some natural products, determining the amount of QUE is crucial. The main objective of this systematic review is to identify the analytical methods validated for detecting and quantifying QUE in different matrices and characterize their sensitivity. A search was conducted until 30 June 2023 in the PubMed database for experimental studies that addressed the validation of chromatographic analytical methods to detect and quantify QUE from consumable natural products. Only studies published between 2018 and 2022, written in English, were included. The risk of bias was assessed by emphasizing methods of comparison according to previously published studies. Descriptive statistics were used to depict the obtained results. The studies were analyzed based on the type of QUE source, chromatographic method, and validation parameters. A total of 17 studies were included in this review. Plants were the most commonly analyzed source of QUE. Among the detection methods, spectrophotometry proved to be the most widely used, surpassing mass spectrometry (MS). After analyzing the bias, all the included studies mentioned/presented, totally or partially, at least four of the eight parameterspt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCarvalho, D., Pinho, C., Oliveira, R., Moreira, F., & Oliveira, A. I. (2023). Chromatographic methods developed for the quantification of quercetin extracted from natural sources: systematic review of published studies from 2018 to 2022. Molecules, 28(23), Artigo 23. https://doi.org/10.3390/molecules28237714pt_PT
dc.identifier.doi10.3390/molecules28237714pt_PT
dc.identifier.eissn1420-3049
dc.identifier.urihttp://hdl.handle.net/10400.22/24921
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/1420-3049/28/23/7714pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAnalytical methodspt_PT
dc.subjectChromatographypt_PT
dc.subjectFlavonoidspt_PT
dc.subjectQuercetinpt_PT
dc.subjectSystematic reviewpt_PT
dc.titleChromatographic methods developed for the quantification of quercetin extracted from natural sources: systematic review of published studies from 2018 to 2022pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue23pt_PT
oaire.citation.startPage7714pt_PT
oaire.citation.titleMoleculespt_PT
oaire.citation.volume28pt_PT
person.familyNamePinho
person.familyNameFerraz Oliveira
person.familyNameMoreira
person.familyNameOliveira
person.givenNameCláudia
person.givenNameRita
person.givenNameFernando
person.givenNameAna Isabel
person.identifier2947760
person.identifier.ciencia-id8B1B-A0D9-B6E4
person.identifier.ciencia-idFD1F-2E0C-1254
person.identifier.ciencia-id5F16-AB92-94D0
person.identifier.ciencia-id9212-F501-E9EF
person.identifier.orcid0000-0002-3157-3712
person.identifier.orcid0000-0003-3933-5740
person.identifier.orcid0000-0002-3452-1459
person.identifier.orcid0000-0003-4420-6476
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication01c994b8-cb20-43a8-947c-d2b978283944
relation.isAuthorOfPublication6c1b7213-1303-47eb-bfa7-ecbef6a9b8d9
relation.isAuthorOfPublication81213e80-09a5-4655-93dc-e54199edb2fe
relation.isAuthorOfPublication4b3fe293-2740-469f-97d3-99d0b107b5e0
relation.isAuthorOfPublication.latestForDiscovery01c994b8-cb20-43a8-947c-d2b978283944

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